U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dcaf12.L DDB1 and CUL4 associated factor 12 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 494761, updated on 17-Aug-2024

Summary

Official Symbol
dcaf12.L
Official Full Name
DDB1 and CUL4 associated factor 12 L homeolog
Primary source
Xenbase:XB-GENE-6078659
Locus tag
XELAEV_18000139mg
See related
EnsemblRapid:ENSXLAG00005001386
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dcaf12; wdr40a; wdr40b; dcaf12-a; dcaf12-b; wdr40a-a
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See dcaf12.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (228727493..228733407)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694904.1 (109773..115712, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene nucleolar protein 6 L homeolog Neighboring gene ubiquitin conjugating enzyme E2 R2 L homeolog Neighboring gene small nucleolar RNA SNORD121A Neighboring gene small nucleolar RNA SNORD121A

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ubiquitin-like ligase-substrate adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of regulation of autophagy ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 
part_of Cul4-RING E3 ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DDB1- and CUL4-associated factor 12-A
Names
WD repeat-containing protein 40A-A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094597.1NP_001088066.1  DDB1- and CUL4-associated factor 12-A

    See identical proteins and their annotated locations for NP_001088066.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082863
    UniProtKB/Swiss-Prot
    Q63ZP7
    UniProtKB/TrEMBL
    A0A974BQS3
    Related
    ENSXLAP00005004215.1, ENSXLAT00005004281.1
    Conserved Domains (3) summary
    COG2319
    Location:98363
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:139175
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:80274
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    228727493..228733407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)