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gemin2.S gem nuclear organelle associated protein 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 494588, updated on 17-Aug-2024

Summary

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Official Symbol
gemin2.S
Official Full Name
gem nuclear organelle associated protein 2 S homeolog
Primary source
Xenbase:XB-GENE-941790
Locus tag
XELAEV_18042638mg
See related
EnsemblRapid:ENSXLAG00005006563
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sip1; gemin2; sip1-delta
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Genomic context

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Location:
chromosome: 8S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (88273249..88288064)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (85896220..85911231)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108700312 Neighboring gene transmembrane protein 87A S homeolog Neighboring gene DNA ligase 1-like Neighboring gene uncharacterized LOC121397795 Neighboring gene protein transport protein Sec23A Neighboring gene rhodopsin, GQ-coupled

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. Fischer U, et al. Cell, 1997 Sep 19. PMID 9323130
  2. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Liu Q, et al. Cell, 1997 Sep 19. PMID 9323129
  3. Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Piazzon N, et al. Nucleic Acids Res, 2013 Jan. PMID 23221635, Free PMC Article
  4. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  5. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spliceosomal complex assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spliceosomal snRNP assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spliceosomal snRNP assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in Gemini of coiled bodies IEA
Inferred from Electronic Annotation
more info
  
part_of SMN complex IEA
Inferred from Electronic Annotation
more info
  
part_of SMN complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of SMN-Sm protein complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
gem-associated protein 2
Names
SMN-interacting protein 1
Survival of motor neuron protein-interacting protein 1
component of gems 2
gem (nuclear organelle) associated protein 2
gemin-2
survival of motor neuron protein interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094476.1 → NP_001087945.2  gem-associated protein 2

    Status: PROVISIONAL

    Source sequence(s)
    BC077574
    UniProtKB/TrEMBL
    A0A8J0Q0J7, A0A974H6I9
    Related
    ENSXLAP00005019527.1, ENSXLAT00005019862.1
    Conserved Domains (1) summary
    pfam04938
    Location:17 → 257
    SIP1; Survival motor neuron (SMN) interacting protein 1 (SIP1)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    88273249..88288064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O42260.1 GenPept UniProtKB/Swiss-Prot:O42260

Gene LinkOut

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