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NUCB2 nucleobindin 2 [ Homo sapiens (human) ]

Gene ID: 4925, updated on 14-Jun-2018
Official Symbol
NUCB2provided by HGNC
Official Full Name
nucleobindin 2provided by HGNC
Primary source
HGNC:HGNC:8044
See related
Ensembl:ENSG00000070081 MIM:608020; Vega:OTTHUMG00000166050
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NEFA; HEL-S-109
Summary
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains. [provided by RefSeq, Oct 2011]
Expression
Broad expression in bone marrow (RPKM 51.4), salivary gland (RPKM 41.2) and 24 other tissues See more
Orthologs
mouse all
See NUCB2 in Genome Data Viewer
Location:
11p15.1
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (17260337..17349980)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (17281884..17371510)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Neighboring gene ribosomal protein L29 pseudogene 21 Neighboring gene ribosomal protein S2 pseudogene 40 Neighboring gene uncharacterized LOC105376576 Neighboring gene natural killer cell cytotoxicity receptor 3 ligand 1 Neighboring gene uncharacterized LOC107984316

Go to nucleotide: Graphics FASTA GenBank

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Related articles in PubMed

  1. Plasma nesfatin 1 level in patients with first attack psychosis. Sahpolat M, et al. Bratisl Lek Listy, 2017. PMID 28814086
  2. Cardioprotective effect of nesfatin-1 against isoproterenol-induced myocardial infarction in rats: Role of the Akt/GSK-3β pathway. Tasatargil A, et al. Peptides, 2017 Sep. PMID 28720397
  3. High expression of nucleobindin 2 is associated with poor prognosis in gastric cancer. Altan B, et al. Tumour Biol, 2017 Jul. PMID 28714371
  4. Serum levels of nesfatin-1 are increased in gestational diabetes mellitus. Zhang Y, et al. Gynecol Endocrinol, 2017 Aug. PMID 28361552
  5. Alterations of circulating NUCB2/nesfatin-1 during short term therapeutic improvement of anxiety in obese inpatients. Hofmann T, et al. Psychoneuroendocrinology, 2017 May. PMID 28273586

See all (113) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  1. Data suggest that levels of nesfatin-1 in maternal serum and cord blood are up-regulated in women with gestational diabetes (GD) as compared to control pregnant women; nesfatin-1 also appears to be up-regulated in subcutaneous abdominal adipose tissue in GD. This study was conducted in China in women of the Han ethnicity.
    Title: Serum levels of nesfatin-1 are increased in gestational diabetes mellitus.
  2. expressions of p-Akt/Akt and p-GSK-3beta/GSK-3beta in the myocardium of MI group rats were significantly increased by nesfatin-1 administration, suggesting that nesfatin-1, which appears to possess anti-apoptotic and anti-inflammatory properties, may confer protection against ISO-induced MI via an Akt/GSK-3beta-dependent mechanism.
    Title: Cardioprotective effect of nesfatin-1 against isoproterenol-induced myocardial infarction in rats: Role of the Akt/GSK-3β pathway.
  3. Study demonstrated that high expression level of NUCB2 was significantly associated with poor clinical outcome of patient with non-metastatic clear cell renal cell carcinoma.
    Title: High NUCB2 expression level represents an independent negative prognostic factor in Chinese cohorts of non-metastatic clear cell renal cell carcinoma patients.
  4. The multifunctional biological actions of nesfatin-1 propelled this peptide as a therapeutic target, and as a potential biomarker of diseases. However, a better and comprehensive understanding of tissue specific effects of nesfatin-1 is critical prior to exploring its possible use in the detection and treatment of diseases.
    Title: Metabolic and Cardiovascular Actions of Nesfatin-1: Implications in Health and Disease.
  5. Data indicate that nesfatin-1/NUCB-2 enhanced migration, invasion and epithelial-mesenchymal transition (EMT) in colon cancer cells through LKB1/AMPK/TORC1/ZEB1 pathways in vitro and in vivo.
    Title: Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer.
  6. Nesfatin-1 levels decrease following biliopancreatic diversion with duodenal switch-induced weight loss and are significantly associated with parameters of metabolic health.
    Title: Association between nesfatin-1 levels and metabolic improvements in severely obese patients who underwent biliopancreatic derivation with duodenal switch.
  7. women and men showed an inverse association between NUCB2/nesfatin-1 and anxiety with a positive correlation in women and a negative correlation in men. However, no significant change of NUCB2/nesfatin-1 following improvement of anxiety has been observed.
    Title: Alterations of circulating NUCB2/nesfatin-1 during short term therapeutic improvement of anxiety in obese inpatients.
  8. Our study was the first to investigate the nesfatin 1 levels in patients with the first episode psychosis. Based on our study results, nesfatin 1 might be related to some central nervous system pathologies, including the severity of a psychiatric disorder.
    Title: Plasma nesfatin 1 level in patients with first attack psychosis.
  9. nucleobindin 2 might play a crucial role in gastric cancer development and could serve as an independent predictor of prognosis of gastric cancer patients.
    Title: High expression of nucleobindin 2 is associated with poor prognosis in gastric cancer.
  10. Based on the obtained results, it was proposed that ghrelin may be considered as playing a role in the etiopathogenesis of hyperemesis gravidarum that may result in disruption of the relationship between nesfatin-1 and ghrelin.
    Title: Concentrations of prealbumin and some appetite-controlling hormones in pregnancies associated with hyperemesis gravidarium.
Submit: New GeneRIF Correction See all GeneRIFs (87)

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

NHGRI GWAS Catalog

Description
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
NHGRI GWA Catalog

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ39156

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
  
calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
cytosol TAS
Traceable Author Statement
more info
 PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
endoplasmic reticulum-Golgi intermediate compartment IDA
Inferred from Direct Assay
more info
 PubMed 
extracellular exosome HDA PubMed 
extracellular space HDA PubMed 
nuclear envelope IEA
Inferred from Electronic Annotation
more info
  
plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
Preferred Names
nucleobindin-2
Names
DNA-binding protein NEFA
epididymis secretory protein Li 109
gastric cancer antigen Zg4
nesfatin 1
nucleobinding 2
prepronesfatin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330227.2 → NP_001317156.1  nucleobindin-2 isoform 2 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS81556.1
    UniProtKB/TrEMBL
    Q2L696
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  2. NM_001352661.1 → NP_001339590.1  nucleobindin-2 isoform 3 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  3. NM_001352662.1 → NP_001339591.1  nucleobindin-2 isoform 4 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Conserved Domains (1) summary
    cl25602
    Location:259 → 370
    DUF3552; Domain of unknown function (DUF3552)

  4. NM_001352663.1 → NP_001339592.1  nucleobindin-2 isoform 3 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  5. NM_001352664.1 → NP_001339593.1  nucleobindin-2 isoform 1 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  6. NM_001352665.1 → NP_001339594.1  nucleobindin-2 isoform 2 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS81556.1
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  7. NM_001352666.1 → NP_001339595.1  nucleobindin-2 isoform 2 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS81556.1
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  8. NM_001352667.1 → NP_001339596.1  nucleobindin-2 isoform 2 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS81556.1
    Related
    ENSP00000408702.2, ENST00000458064.6
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  9. NM_001352668.1 → NP_001339597.1  nucleobindin-2 isoform 1 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  10. NM_001352669.1 → NP_001339598.1  nucleobindin-2 isoform 1 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  11. NM_001352670.1 → NP_001339599.1  nucleobindin-2 isoform 1 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  12. NM_001352671.1 → NP_001339600.1  nucleobindin-2 isoform 2 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS81556.1
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  13. NM_001352672.1 → NP_001339601.1  nucleobindin-2 isoform 1 preproprotein

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  14. NM_005013.3 → NP_005004.1  nucleobindin-2 isoform 1 preproprotein

    See identical proteins and their annotated locations for NP_005004.1

    Status: VALIDATED

    Source sequence(s)
    AC107956, KF455328
    Consensus CDS
    CCDS41623.1
    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Related
    ENSP00000436455.1, OTTHUMP00000231794, ENST00000529010.5
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    17260337..17349980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448537.1 → XP_024304305.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  2. XM_024448544.1 → XP_024304312.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  3. XM_017017815.1 → XP_016873304.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  4. XM_024448546.1 → XP_024304314.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  5. XM_024448543.1 → XP_024304311.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  6. XM_024448527.1 → XP_024304295.1  nucleobindin-2 isoform X1

    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  7. XM_024448548.1 → XP_024304316.1  nucleobindin-2 isoform X4

    Conserved Domains (1) summary
    cl25602
    Location:259 → 370
    DUF3552; Domain of unknown function (DUF3552)

  8. XM_024448551.1 → XP_024304319.1  nucleobindin-2 isoform X5

    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  9. XM_024448533.1 → XP_024304301.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  10. XM_024448528.1 → XP_024304296.1  nucleobindin-2 isoform X1

    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  11. XM_024448550.1 → XP_024304318.1  nucleobindin-2 isoform X5

    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  12. XM_024448532.1 → XP_024304300.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  13. XM_017017818.2 → XP_016873307.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Related
    ENSP00000481959.1, ENST00000622082.4
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  14. XM_024448535.1 → XP_024304303.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  15. XM_017017826.1 → XP_016873315.1  nucleobindin-2 isoform X7

    UniProtKB/TrEMBL
    Q2L696
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  16. XM_024448554.1 → XP_024304322.1  nucleobindin-2 isoform X6

    Conserved Domains (1) summary
    cl25602
    Location:259 → 370
    DUF3552; Domain of unknown function (DUF3552)

  17. XM_024448553.1 → XP_024304321.1  nucleobindin-2 isoform X5

    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  18. XM_024448549.1 → XP_024304317.1  nucleobindin-2 isoform X5

    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  19. XM_024448531.1 → XP_024304299.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  20. XM_024448530.1 → XP_024304298.1  nucleobindin-2 isoform X1

    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  21. XM_024448547.1 → XP_024304315.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  22. XM_024448540.1 → XP_024304308.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  23. XM_017017828.1 → XP_016873317.1  nucleobindin-2 isoform X7

    UniProtKB/TrEMBL
    Q2L696
    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  24. XM_017017814.1 → XP_016873303.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  25. XM_024448542.1 → XP_024304310.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  26. XM_017017812.2 → XP_016873301.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  27. XM_024448538.1 → XP_024304306.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  28. XM_024448541.1 → XP_024304309.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  29. XM_024448552.1 → XP_024304320.1  nucleobindin-2 isoform X5

    Conserved Domains (1) summary
    cl25602
    Location:258 → 369
    DUF3552; Domain of unknown function (DUF3552)

  30. XM_024448539.1 → XP_024304307.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  31. XM_017017813.1 → XP_016873302.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  32. XM_024448529.1 → XP_024304297.1  nucleobindin-2 isoform X1

    Conserved Domains (2) summary
    pfam13499
    Location:248 → 324
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:306 → 399
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  33. XM_024448536.1 → XP_024304304.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  34. XM_024448534.1 → XP_024304302.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  35. XM_017017817.1 → XP_016873306.1  nucleobindin-2 isoform X3

    UniProtKB/Swiss-Prot
    P80303
    UniProtKB/TrEMBL
    V9HW75
    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  36. XM_024448545.1 → XP_024304313.1  nucleobindin-2 isoform X2

    Conserved Domains (2) summary
    pfam13499
    Location:247 → 323
    EF-hand_7; EF-hand domain pair
    cl25632
    Location:305 → 398
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_132751.1: Suppressed sequence

    Description
    NR_132751.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P80303.3 GenPept UniProtKB/Swiss-Prot:P80303

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