PFKP phosphofructokinase, platelet [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PFKPprovided by VGNC
Official Full Name: phosphofructokinase, plateletprovided by VGNC
Primary source: VGNC:VGNC:44448
See related: Ensembl:ENSCAFG00845003297
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	2	NC_051806.1 (32603570..32647286, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	2	NC_006584.4 (29249439..29293199, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	2	NC_049223.1 (31255597..31299277, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	2	NC_049262.1 (29690270..29734042, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	2	NC_049743.1 (30527797..30571404, complement)

Chromosome 2 - NC_051806.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 6-phosphofructokinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables AMP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables fructose-6-phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables identical protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monosaccharide binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical glycolysis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose 1,6-bisphosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose 6-phosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of 6-phosphofructokinase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 6-phosphofructokinase type C; ATP-dependent 6-phosphofructokinase, platelet type

XP_038313490.1

EC 2.7.1.11

XP_038313495.1

EC 2.7.1.11

XP_038313498.1

EC 2.7.1.11

XP_038313499.1

EC 2.7.1.11

XP_038325381.1

EC 2.7.1.11

XP_038325382.1

EC 2.7.1.11

XP_038325383.1

EC 2.7.1.11

XP_038325384.1

EC 2.7.1.11

XP_038386143.1

EC 2.7.1.11

XP_038386144.1

EC 2.7.1.11

XP_038386145.1

EC 2.7.1.11

XP_038386146.1

EC 2.7.1.11

XP_038450390.1

EC 2.7.1.11

XP_038450391.1

EC 2.7.1.11

XP_038450392.1

EC 2.7.1.11

XP_038450393.1

EC 2.7.1.11

XP_038514435.1

EC 2.7.1.11

XP_038514436.1

EC 2.7.1.11

XP_038514437.1

EC 2.7.1.11

XP_038514438.1

EC 2.7.1.11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051806.1 Reference ROS_Cfam_1.0

Range

32603570..32647286 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038658510.1 → XP_038514438.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4

UniProtKB/TrEMBL

A0A8C0Q099, A0A8I3MV50

Related

ENSCAFP00845004744.1, ENSCAFT00845005961.1

Conserved Domains (1) summary

cl00204
Location:22 → 728

PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
XM_038658509.1 → XP_038514437.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3

UniProtKB/TrEMBL

A0A8I3MP53, A0A8I3MV60, A0A8P0P5T2

Related

ENSCAFP00845004780.1, ENSCAFT00845006017.1

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038658508.1 → XP_038514436.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X2

UniProtKB/TrEMBL

A0A8C0JT26, A0A8I3MPH7, A0A8P0SAZ7, A0A8P0T2M8

Related

ENSCAFP00845004638.1, ENSCAFT00845005840.1

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038658507.1 → XP_038514435.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X1

UniProtKB/TrEMBL

A0A8C0PRV8

Related

ENSCAFP00845004649.1, ENSCAFT00845005852.1

Conserved Domains (1) summary

cd00764
Location:22 → 830

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049262.1 Alternate UMICH_Zoey_3.1

Range

29690270..29734042 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038469456.1 → XP_038325384.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4

Conserved Domains (1) summary

cl00204
Location:22 → 728

PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
XM_038469455.1 → XP_038325383.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3
XM_038469454.1 → XP_038325382.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X2

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038469453.1 → XP_038325381.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049743.1 Alternate UNSW_CanFamBas_1.0

Range

30527797..30571404 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038594465.1 → XP_038450393.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4

Conserved Domains (1) summary

cl00204
Location:22 → 728

PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
XM_038594464.1 → XP_038450392.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038594463.1 → XP_038450391.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X2

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038594462.1 → XP_038450390.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X1

Conserved Domains (1) summary

cd00764
Location:22 → 830

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049223.1 Alternate UU_Cfam_GSD_1.0

Range

31255597..31299277 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038530218.1 → XP_038386146.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4

UniProtKB/TrEMBL

A0A8C0Q099, A0A8I3MV50

Conserved Domains (1) summary

cl00204
Location:22 → 728

PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
XM_038530217.1 → XP_038386145.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3

UniProtKB/TrEMBL

A0A8C0RVV9
XM_038530216.1 → XP_038386144.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X2

UniProtKB/TrEMBL

A0A8C0JT26, A0A8I3MPH7, A0A8P0SAZ7, A0A8P0T2M8

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038530215.1 → XP_038386143.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X1

UniProtKB/TrEMBL

A0A8C0PRV8

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

29249439..29293199 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038457571.1 → XP_038313499.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X4

UniProtKB/TrEMBL

A0A8C0Q099, A0A8I3MV50

Conserved Domains (1) summary

cl00204
Location:22 → 728

PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
XM_038457570.1 → XP_038313498.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X3

UniProtKB/TrEMBL

A0A8I3MP53, A0A8I3MV60, A0A8P0P5T2

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038457567.1 → XP_038313495.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X2

UniProtKB/TrEMBL

A0A8C0JT26, A0A8I3MPH7, A0A8P0SAZ7, A0A8P0T2M8

Conserved Domains (1) summary

cd00764
Location:22 → 779

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
XM_038457562.1 → XP_038313490.1 ATP-dependent 6-phosphofructokinase, platelet type isoform X1

UniProtKB/TrEMBL

A0A8C0PRV8

Conserved Domains (1) summary

cd00764
Location:22 → 830

Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...