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GATA4 GATA binding protein 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 472698, updated on 17-Aug-2024

Summary

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Official Symbol
GATA4provided by VGNC
Official Full Name
GATA binding protein 4provided by VGNC
Primary source
VGNC:VGNC:50427
Locus tag
CK820_G0040355
See related
Ensembl:ENSPTRG00000019993
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (17697434..17753118)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (20812705..20895724)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene BLK proto-oncogene, Src family tyrosine kinase Neighboring gene uncharacterized LOC134810816 Neighboring gene uncharacterized LOC104004257 Neighboring gene putative uncharacterized protein C8orf49 Neighboring gene nei like DNA glycosylase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell fate commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor GATA-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    17697434..17753118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009440250.5 → XP_009438525.2  transcription factor GATA-4 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SFW5, A0A2I3TK78, A0A2J8Q9B5, A0A6D2WMY4
    Conserved Domains (2) summary
    cd00202
    Location:271 → 322
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:1 → 205
    GATA-N; GATA-type transcription activator, N-terminal

  2. XM_009440249.5 → XP_009438524.2  transcription factor GATA-4 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TK78, A0A2J8Q9B1, A0A6D2VWI2, H2QVR5
    Related
    ENSPTRP00000034232.5
    Conserved Domains (2) summary
    cd00202
    Location:270 → 321
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:1 → 205
    GATA-N; GATA-type transcription activator, N-terminal
Nucleotide Protein
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