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MYBPH myosin binding protein H [ Homo sapiens (human) ]

Gene ID: 4608, updated on 1-Jun-2020

Summary

Official Symbol
MYBPHprovided by HGNC
Official Full Name
myosin binding protein Hprovided by HGNC
Primary source
HGNC:HGNC:7552
See related
Ensembl:ENSG00000133055 MIM:160795
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in prostate (RPKM 3.0), kidney (RPKM 0.5) and 4 other tissues See more
Orthologs

Genomic context

See MYBPH in Genome Data Viewer
Location:
1q32.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (203167811..203175826, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (203136939..203144969, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene myogenin promoter associated myogenic regulatory antisense long non coding RNA Neighboring gene myogenin Neighboring gene adenosine A1 receptor Neighboring gene chitinase 3 like 1 Neighboring gene chitinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural constituent of muscle TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
regulation of striated muscle contraction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
myosin filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
myosin-binding protein H
Names
H-protein
myBP-H

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004997.3NP_004988.2  myosin-binding protein H

    See identical proteins and their annotated locations for NP_004988.2

    Status: VALIDATED

    Source sequence(s)
    AC105940, BC044226, L05606
    Consensus CDS
    CCDS30975.1
    UniProtKB/Swiss-Prot
    Q13203
    Related
    ENSP00000255416.4, ENST00000255416.9
    Conserved Domains (4) summary
    cd00063
    Location:267355
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:382471
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:191263
    Ig; Immunoglobulin domain
    cl28408
    Location:469
    UBQ; Ubiquitin homologues

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    203167811..203175826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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