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PCK1 phosphoenolpyruvate carboxykinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 458362, updated on 2-Nov-2023

Summary

Official Symbol
PCK1provided by VGNC
Official Full Name
phosphoenolpyruvate carboxykinase 1provided by VGNC
Primary source
VGNC:VGNC:6228
Locus tag
CK820_G0048814
See related
Ensembl:ENSPTRG00000013664
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See PCK1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (63908011..63913382)

Chromosome 20 - NC_072418.1Genomic Context describing neighboring genes Neighboring gene putative high mobility group protein B1-like 1 Neighboring gene CCCTC-binding factor like Neighboring gene Z-DNA binding protein 1 Neighboring gene prostate transmembrane protein, androgen induced 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072418.1 Chromosome 20 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Names
cytosolic phosphoenolpyruvate carboxykinase 1
phosphoenolpyruvate carboxykinase 1 (soluble)
XP_009435729.1
XP_514745.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072418.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    63908011..63913382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_514745.8XP_514745.2  phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1

    UniProtKB/TrEMBL
    A0A2J8JCD0, A0A6D2Y8T2, H2QKN1
    Related
    ENSPTRP00000023500.2
    Conserved Domains (1) summary
    cd00819
    Location:27615
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
  2. XM_009437454.3XP_009435729.1  phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X2

    Conserved Domains (1) summary
    cd00819
    Location:4483
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...