DLST dihydrolipoamide S-succinyltransferase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: DLSTprovided by VGNC
Official Full Name: dihydrolipoamide S-succinyltransferaseprovided by VGNC
Primary source: VGNC:VGNC:9156
Locus tag: CK820_G0002903
See related: Ensembl:ENSPTRG00000006543
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	15	NC_072413.2 (72832439..72854306)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	14	NC_072412.1 (66127723..66149573)

Chromosome 15 - NC_072413.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G10732 (e-PCR)
- UniSTS:26430

PMC162151P1 (e-PCR)
- UniSTS:271453

PMC162151P2 (e-PCR)
- UniSTS:271454

PMC162151P3 (e-PCR)
- UniSTS:271455

PMC162151P4 (e-PCR)
- UniSTS:271456

SHGC-37068 (e-PCR)
- UniSTS:8076

RH70222 (e-PCR)
- UniSTS:24799

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables dihydrolipoyllysine-residue succinyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed
part_of oxoglutarate dehydrogenase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

Names: dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

XP_003952588.2

EC 2.3.1.61

XP_009426423.2

EC 2.3.1.61

XP_009426424.2

EC 2.3.1.61

XP_016781917.1

EC 2.3.1.61

XP_016781918.1

EC 2.3.1.61

XP_016781920.1

EC 2.3.1.61

XP_063649790.1

EC 2.3.1.61

XP_063649791.1

EC 2.3.1.61

XP_510068.3

EC 2.3.1.61

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

72832439..72854306

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016926428.3 → XP_016781917.1 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1

Related

ENSPTRP00000079368.1
XM_510068.9 → XP_510068.3 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A2J8PJU0, A0A6D2XZM2, H2Q8M1, K7BEL6, K7BR09

Related

ENSPTRP00000011110.4

Conserved Domains (1) summary

TIGR01347
Location:71 → 453

sucB; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component)
XM_009428148.5 → XP_009426423.2 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X4

UniProtKB/TrEMBL

K7BR09
XM_016926429.4 → XP_016781918.1 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X3

UniProtKB/TrEMBL

K7BR09
XM_009428149.4 → XP_009426424.2 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X6

Conserved Domains (1) summary

pfam00198
Location:55 → 268

2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
XM_016926431.4 → XP_016781920.1 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X5

Conserved Domains (2) summary

pfam00198
Location:152 → 365

2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)

cl11404
Location:24 → 57

Biotinyl_lipoyl_domains; Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
XM_003952539.6 → XP_003952588.2 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X6

Conserved Domains (1) summary

pfam00198
Location:55 → 268

2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
XM_063793720.1 → XP_063649790.1 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X5
XM_063793721.1 → XP_063649791.1 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X6