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PRPF19 pre-mRNA processing factor 19 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451228, updated on 17-Aug-2024

Summary

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Official Symbol
PRPF19provided by VGNC
Official Full Name
pre-mRNA processing factor 19provided by VGNC
Primary source
VGNC:VGNC:1039
Locus tag
CK820_G0030874
See related
Ensembl:ENSPTRG00000003724
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (63142418..63158502, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (62251947..62267850, complement)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 86 Neighboring gene prostaglandin D2 receptor 2 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene uncharacterized LOC134807350 Neighboring gene uncharacterized LOC107967098 Neighboring gene transmembrane protein 109

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Prp19 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of U2-type catalytic step 1 spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pre-mRNA-processing factor 19
Names
PRP19/PSO4 pre-mRNA processing factor 19 homolog
XP_001142421.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    63142418..63158502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001142421.7 → XP_001142421.1  pre-mRNA-processing factor 19

    See identical proteins and their annotated locations for XP_001142421.1

    UniProtKB/TrEMBL
    A0A2I3TJG2, A0A2J8LCZ1, A0A6D2XB23, H2Q3T2
    Related
    ENSPTRP00000006406.4
    Conserved Domains (4) summary
    cd00200
    Location:223 → 503
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:224 → 262
    7WD40; WD40 repeat [structural motif]
    cd16656
    Location:4 → 56
    RING-Ubox_PRP19; U-box domain, a modified RING finger, found in pre-mRNA-processing factor 19 (Prp19) and similar proteins
    pfam08606
    Location:69 → 133
    Prp19; Prp19/Pso4-like
Nucleotide Protein
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Molecular Biology Databases
Research Materials