U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LEP leptin [ Pan troglodytes (chimpanzee) ]

Gene ID: 449638, updated on 2-Nov-2023

Summary

Official Symbol
LEPprovided by VGNC
Official Full Name
leptinprovided by VGNC
Primary source
VGNC:VGNC:53278
Locus tag
CK820_G0011676
See related
Ensembl:ENSPTRG00000047519
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
OB
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LEP in Genome Data Viewer
Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (137722558..137739204)

Chromosome 7 - NC_072405.1Genomic Context describing neighboring genes Neighboring gene staphylococcal nuclease and tudor domain containing 1 Neighboring gene microRNA mir-593 Neighboring gene microRNA mir-129-1 Neighboring gene U7 small nuclear RNA Neighboring gene RNA binding motif protein 28

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072405.1 Chromosome 7 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables peptide hormone receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
leptin
Names
leptin (obesity homolog, mouse)
obesity factor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193672.1NP_001180601.1  leptin precursor

    See identical proteins and their annotated locations for NP_001180601.1

    Status: PROVISIONAL

    Source sequence(s)
    JAQQLN010000033, U96450
    UniProtKB/Swiss-Prot
    O02750
    UniProtKB/TrEMBL
    A0A2J8QWY9, A0A6D2Y975, H2QVB5
    Conserved Domains (1) summary
    pfam02024
    Location:26167
    Leptin; Leptin

RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072405.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    137722558..137739204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009454014.3XP_009452289.1  leptin isoform X1

    See identical proteins and their annotated locations for XP_009452289.1

    UniProtKB/Swiss-Prot
    O02750
    UniProtKB/TrEMBL
    A0A2J8QWY9, A0A6D2Y975, H2QVB5
    Related
    ENSPTRP00000072740.1
    Conserved Domains (1) summary
    pfam02024
    Location:26167
    Leptin; Leptin