myl2.S myosin light chain 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: myl2.S
Official Full Name: myosin light chain 2 S homeolog
Primary source: Xenbase:XB-GENE-864827
Locus tag: XELAEV_18010667mg
See related: EnsemblRapid:ENSXLAG00005007570
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mlc2; myl2; XMLC2; cmh10
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Genomic context

Location:: chromosome: 1S

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (151648673..151657100)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (135873236..135881663)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cardiac muscle contraction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within heart development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within muscle cell fate specification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in myofibril	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: myosin light chain 2 S homeolog

Names: myosin, light chain 2, regulatory, cardiac, slow

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093839.1 → NP_001087308.1 myosin light chain 2 S homeolog

See identical proteins and their annotated locations for NP_001087308.1

Status: PROVISIONAL

Source sequence(s)

BC078537

UniProtKB/TrEMBL

A0A974I1Z9, Q66KW3

Related

ENSXLAP00005021462.1, ENSXLAT00005022153.1

Conserved Domains (2) summary

COG5126
Location:8 → 163

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cl08302
Location:28 → 73

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...