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myl2.S myosin light chain 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447131, updated on 8-Apr-2017

Summary

Official Symbol
myl2.S
Official Full Name
myosin light chain 2 S homeolog
Primary source
Xenbase:XB-GENE-864827
Locus tag
XELAEV_18010667mg
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
mlc2; myl2; XMLC2; cmh10

Genomic context

See myl2.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
7
Annotation release Status Assembly Chr Location
100 current Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (135873236..135881663)

Chromosome 1S - NC_030725.1Genomic Context describing neighboring genes Neighboring gene sesquipedalian-1-like Neighboring gene cut like homeobox 2 S homeolog Neighboring gene mitogen-activated protein kinase-activated protein kinase 5 S homeolog Neighboring gene transmembrane protein 116-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_030725.1 Chromosome 1S Reference Xenopus_laevis_v2 Primary Assembly

Pathways from BioSystems

  • Adrenergic signaling in cardiomyocytes, organism-specific biosystem (from KEGG)
    Adrenergic signaling in cardiomyocytes, organism-specific biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
  • Adrenergic signaling in cardiomyocytes, conserved biosystem (from KEGG)
    Adrenergic signaling in cardiomyocytes, conserved biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
  • Apelin signaling pathway, organism-specific biosystem (from KEGG)
    Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
  • Cardiac muscle contraction, organism-specific biosystem (from KEGG)
    Cardiac muscle contraction, organism-specific biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
  • Cardiac muscle contraction, conserved biosystem (from KEGG)
    Cardiac muscle contraction, conserved biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
    Regulation of actin cytoskeleton, organism-specific biosystem
    Regulation of actin cytoskeleton
  • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
    Regulation of actin cytoskeleton, conserved biosystem
    Regulation of actin cytoskeleton
  • Tight junction, organism-specific biosystem (from KEGG)
    Tight junction, organism-specific biosystemTight junctions (TJs) are essential for establishing a selectively permeable barrier to diffusion through the paracellular space between neighboring cells. TJs are composed of at least three types of...
  • Tight junction, conserved biosystem (from KEGG)
    Tight junction, conserved biosystemTight junctions (TJs) are essential for establishing a selectively permeable barrier to diffusion through the paracellular space between neighboring cells. TJs are composed of at least three types of...

General protein information

Preferred Names
myosin light chain 2 S homeolog
Names
myosin, light chain 2, regulatory, cardiac, slow

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093839.1NP_001087308.1  myosin light chain 2 S homeolog

    See identical proteins and their annotated locations for NP_001087308.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078537
    UniProtKB/TrEMBL
    Q66KW3
    Conserved Domains (2) summary
    COG5126
    Location:8163
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cl08302
    Location:2873
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v2 Primary Assembly

Genomic

  1. NC_030725.1 Reference Xenopus_laevis_v2 Primary Assembly

    Range
    135873236..135881663
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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