U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

krt97 keratin 97 [ Danio rerio (zebrafish) ]

Gene ID: 436656, updated on 12-Sep-2024

Summary

Official Symbol
krt97provided by ZNC
Official Full Name
keratin 97provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-78
See related
Ensembl:ENSDARG00000000212 AllianceGenome:ZFIN:ZDB-GENE-040718-78
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb112; sb:cb112; sb:cb481; zgc:92061; wu:fa91g11
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in several structures, including EVL; fin; hatching gland; integument; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive woolly hair 3; ectodermal dysplasia (multiple); epidermolytic hyperkeratosis; hereditary mucosal leukokeratosis; and palmoplantar keratosis (multiple). Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (11756057..11759106)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (11726375..11729424)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene crystallin, gamma S1 Neighboring gene keratin 222 Neighboring gene keratin 96 Neighboring gene protein tyrosine phosphatase non-receptor type 4b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin 97
Names
cytokeratin E7
krt17
type I keratin E7

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002383.1NP_001002383.1  keratin 97

    See identical proteins and their annotated locations for NP_001002383.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075874
    UniProtKB/TrEMBL
    A0A8M1N0G0, Q6DHU3
    Related
    ENSDARP00000096586.3, ENSDART00000105808.4
    Conserved Domains (1) summary
    pfam00038
    Location:78387
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    11756057..11759106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)