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Plcxd2 phosphatidylinositol-specific phospholipase C, X domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 433022, updated on 18-Apr-2024

Summary

Official Symbol
Plcxd2provided by MGI
Official Full Name
phosphatidylinositol-specific phospholipase C, X domain containing 2provided by MGI
Primary source
MGI:MGI:3647874
See related
Ensembl:ENSMUSG00000087141 AllianceGenome:MGI:3647874
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG433022
Summary
Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within lipid catabolic process and signal transduction. Predicted to be located in nucleus. Is expressed in alimentary system; limb; liver; nervous system; and retina. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 12.6), cortex adult (RPKM 10.3) and 17 other tissues See more
Orthologs
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Genomic context

Location:
16 B5; 16 30.45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (45779624..45830776, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (45959261..46010413, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_40921 Neighboring gene abhydrolase domain containing 10 Neighboring gene pleckstrin homology like domain, family B, member 2 Neighboring gene STARR-seq mESC enhancer starr_40922 Neighboring gene predicted gene 15638 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:46006394-46006690 Neighboring gene STARR-positive B cell enhancer ABC_E4173 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:46011002-46011185 Neighboring gene predicted gene, 24754 Neighboring gene predicted gene, 31198

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PI-PLC X domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134480.1NP_001127952.1  PI-PLC X domain-containing protein 2

    See identical proteins and their annotated locations for NP_001127952.1

    Status: VALIDATED

    Source sequence(s)
    BC049364, BC151059, CJ104359
    Consensus CDS
    CCDS49863.1
    UniProtKB/Swiss-Prot
    B2RXA1
    Related
    ENSMUSP00000114852.2, ENSMUST00000130481.2
    Conserved Domains (1) summary
    cd08616
    Location:39329
    PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    45779624..45830776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)