SPIRE1 spire type actin nucleation factor 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: SPIRE1provided by CGNC
Full Name: spire type actin nucleation factor 1provided by CGNC
Primary source: CGNC:10340
See related: Ensembl:ENSGALG00010001180
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (96643502..96768712)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (96720596..96846046)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi vesicle transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin filament network formation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin filament polymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin nucleation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cleavage furrow formation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment of meiotic spindle localization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in polar body extrusion after meiotic divisions	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell cortex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasmic vesicle membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein spire homolog 1

Names: spire homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

96643502..96768712

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040696641.2 → XP_040552575.1 protein spire homolog 1 isoform X1

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (3) summary

PRK13335
Location:427 → 553

PRK13335; superantigen-like protein SSL3; Reviewed

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:640 → 769

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040696644.2 → XP_040552578.1 protein spire homolog 1 isoform X5

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:582 → 711

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040696642.2 → XP_040552576.1 protein spire homolog 1 isoform X2

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:635 → 764

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040696643.2 → XP_040552577.1 protein spire homolog 1 isoform X3

UniProtKB/TrEMBL

A0A8V0X4G2

Related

ENSGALP00010001276.1, ENSGALT00010002726.1

Conserved Domains (3) summary

PRK13335
Location:413 → 539

PRK13335; superantigen-like protein SSL3; Reviewed

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:626 → 755

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_025147816.3 → XP_025003584.2 protein spire homolog 1 isoform X6

UniProtKB/TrEMBL

A0A8V0X1G9, A0A8V0X4G2

Related

ENSGALP00010001277.1, ENSGALT00010002727.1

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:568 → 697

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_046938002.1 → XP_046793958.1 protein spire homolog 1 isoform X4

UniProtKB/TrEMBL

A0A8V0X4G2
XM_040696645.2 → XP_040552579.1 protein spire homolog 1 isoform X7

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:563 → 692

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

96720596..96846046

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040664833.2 → XP_040520767.1 protein spire homolog 1 isoform X1

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (3) summary

PRK13335
Location:427 → 553

PRK13335; superantigen-like protein SSL3; Reviewed

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:640 → 769

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040664836.2 → XP_040520770.1 protein spire homolog 1 isoform X5

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:582 → 711

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040664834.2 → XP_040520768.1 protein spire homolog 1 isoform X2

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:635 → 764

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040664835.2 → XP_040520769.1 protein spire homolog 1 isoform X3

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (3) summary

PRK13335
Location:413 → 539

PRK13335; superantigen-like protein SSL3; Reviewed

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:626 → 755

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_040664837.2 → XP_040520771.1 protein spire homolog 1 isoform X6

UniProtKB/TrEMBL

A0A8V0X1G9, A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:568 → 697

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
XM_046912468.1 → XP_046768424.1 protein spire homolog 1 isoform X4

UniProtKB/TrEMBL

A0A8V0X4G2
XM_040664838.2 → XP_040520772.1 protein spire homolog 1 isoform X7

UniProtKB/TrEMBL

A0A8V0X4G2

Conserved Domains (2) summary

smart00750
Location:37 → 227

KIND; kinase non-catalytic C-lobe domain

cd15767
Location:563 → 692

FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins