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MEF2C myocyte enhancer factor 2C [ Homo sapiens (human) ]

Gene ID: 4208, updated on 17-Jun-2018
Official Symbol
MEF2Cprovided by HGNC
Official Full Name
myocyte enhancer factor 2Cprovided by HGNC
Primary source
HGNC:HGNC:6996
See related
Ensembl:ENSG00000081189 MIM:600662; Vega:OTTHUMG00000162634
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DEL5q14.3; C5DELq14.3
Summary
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Expression
Broad expression in brain (RPKM 55.2), lymph node (RPKM 17.7) and 19 other tissues See more
Orthologs
See MEF2C in Genome Data Viewer
Location:
5q14.3
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 5 NC_000005.10 (88718241..88904105, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (88014058..88199922, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene TMEM161B antisense RNA 1 Neighboring gene long intergenic non-protein coding RNA 2060 Neighboring gene long intergenic non-protein coding RNA 461 Neighboring gene MEF2C antisense RNA 2 Neighboring gene microRNA 9-2 Neighboring gene uncharacterized LOC107986361 Neighboring gene uncharacterized LOC107986360 Neighboring gene MEF2C antisense RNA 1 Neighboring gene VISTA enhancer hs503

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Mental retardation, stereotypic movements, epilepsy, and/or cerebral malformations
MedGen: C3150700 OMIM: 613443 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

Little evidence for dosage pathogenicity (Last evaluated (2013-02-28)

ClinGen Genome Curation PagePubMed
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated (2013-02-28)

ClinGen Genome Curation PagePubMed

NHGRI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
NHGRI GWA Catalog
Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.
NHGRI GWA Catalog
Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.
NHGRI GWA Catalog
Genetic loci for retinal arteriolar microcirculation.
NHGRI GWA Catalog
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
NHGRI GWA Catalog
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.
NHGRI GWA Catalog
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
NHGRI GWA Catalog
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
NHGRI GWA Catalog
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
NHGRI GWA Catalog
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
NHGRI GWA Catalog
Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm.
NHGRI GWA Catalog
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
NHGRI GWA Catalog
New gene functions in megakaryopoiesis and platelet formation.
NHGRI GWA Catalog
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
NHGRI GWA Catalog
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    miRs in Muscle Cell Differentiation, organism-specific biosystem
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Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
AT DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
HMG box domain binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II activating transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA
Inferred from Sequence Alignment
more info
 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
Inferred from Sequence Model
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
Non-traceable Author Statement
more info
PubMed 
activating transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription regulatory region DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
B cell homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
B cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
B cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
MAPK cascade IDA
Inferred from Direct Assay
more info
PubMed 
MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
blood vessel development ISS
Inferred from Sequence or Structural Similarity
more info
 
blood vessel remodeling ISS
Inferred from Sequence or Structural Similarity
more info
 
cardiac muscle hypertrophy in response to stress IEA
Inferred from Electronic Annotation
more info
 
cardiac ventricle formation ISS
Inferred from Sequence or Structural Similarity
more info
 
cartilage morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cell morphogenesis involved in neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to calcium ion ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to drug ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to fluid shear stress ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to lipopolysaccharide ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to parathyroid hormone stimulus IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to transforming growth factor beta stimulus IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to trichostatin A ISS
Inferred from Sequence or Structural Similarity
more info
 
chondrocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
embryonic viscerocranium morphogenesis IEA
Inferred from Electronic Annotation
more info
 
endochondral ossification ISS
Inferred from Sequence or Structural Similarity
more info
 
epithelial cell proliferation involved in renal tubule morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
excitatory postsynaptic potential ISS
Inferred from Sequence or Structural Similarity
more info
 
germinal center formation ISS
Inferred from Sequence or Structural Similarity
more info
 
glomerulus morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
heart development IEP
Inferred from Expression Pattern
more info
PubMed 
heart development ISS
Inferred from Sequence or Structural Similarity
more info
 
heart development NAS
Non-traceable Author Statement
more info
PubMed 
heart looping ISS
Inferred from Sequence or Structural Similarity
more info
 
humoral immune response ISS
Inferred from Sequence or Structural Similarity
more info
 
learning or memory ISS
Inferred from Sequence or Structural Similarity
more info
 
melanocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
monocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
muscle cell fate determination ISS
Inferred from Sequence or Structural Similarity
more info
 
muscle organ development TAS
Traceable Author Statement
more info
PubMed 
myotube differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of blood vessel endothelial cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of neuron apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of ossification IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of vascular associated smooth muscle cell migration IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of vascular associated smooth muscle cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of vascular endothelial cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of vascular smooth muscle cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of vascular smooth muscle cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
nephron tubule epithelial cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
nervous system development TAS
Traceable Author Statement
more info
PubMed 
neural crest cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
neuron development ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron migration ISS
Inferred from Sequence or Structural Similarity
more info
 
osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
outflow tract morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
platelet formation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of B cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of alkaline phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of behavioral fear response ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of bone mineralization ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cardiac muscle cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cardiac muscle cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cell proliferation in bone marrow IEA
Inferred from Electronic Annotation
more info
 
positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of macrophage apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of muscle cell differentiation TAS
Traceable Author Statement
more info
 
positive regulation of myoblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of skeletal muscle cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of skeletal muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
primary heart field specification ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of AMPA receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of NMDA receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of dendritic spine development ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of germinal center formation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of megakaryocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of neuron apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of neurotransmitter secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of sarcomere organization IEA
Inferred from Electronic Annotation
more info
 
regulation of synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic plasticity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic transmission, glutamatergic ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
renal tubule morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
roof of mouth development IEA
Inferred from Electronic Annotation
more info
 
secondary heart field specification ISS
Inferred from Sequence or Structural Similarity
more info
 
sinoatrial valve morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle tissue development ISS
Inferred from Sequence or Structural Similarity
more info
 
smooth muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
ventricular cardiac muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nuclear chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear speck IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
postsynapse IEA
Inferred from Electronic Annotation
more info
 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
myocyte-specific enhancer factor 2C
Names
MADS box transcription enhancer factor 2, polypeptide C

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_023427.1 RefSeqGene

    Range
    5001..190865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001131005.2NP_001124477.1  myocyte-specific enhancer factor 2C isoform 2

    See identical proteins and their annotated locations for NP_001124477.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    AC008525, AL833268, AL833274, BP231922, L08895
    Consensus CDS
    CCDS47244.1
    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000389610.2, OTTHUMP00000222411, ENST00000424173.6, OTTHUMT00000369818
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  2. NM_001193347.1NP_001180276.1  myocyte-specific enhancer factor 2C isoform 3

    See identical proteins and their annotated locations for NP_001180276.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is longer than isoform 1.
    Source sequence(s)
    AC008525, AL833268, AL833274, BP231922, L08895
    Consensus CDS
    CCDS54878.1
    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000340874.5, OTTHUMP00000222412, ENST00000340208.9, OTTHUMT00000369819
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:117171
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  3. NM_001193348.1NP_001180277.1  myocyte-specific enhancer factor 2C isoform 4

    See identical proteins and their annotated locations for NP_001180277.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks two alternate in-frame exons in the coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1.
    Source sequence(s)
    AC008525, AL833268, FM163484, L08895
    Consensus CDS
    CCDS54877.1
    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000487311.1, OTTHUMP00000278385, ENST00000628656.2, OTTHUMT00000480520
    Conserved Domains (1) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  4. NM_001193349.2NP_001180278.1  myocyte-specific enhancer factor 2C isoform 5

    See identical proteins and their annotated locations for NP_001180278.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 5), compared to isoform 1. Variants 5 and 12 both encode the same isoform (5).
    Source sequence(s)
    AC008525, AC008835
    Consensus CDS
    CCDS78030.1
    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    D8L7E9
    Related
    ENSP00000487184.1, OTTHUMP00000278384, ENST00000626391.2
    Conserved Domains (1) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  5. NM_001193350.1NP_001180279.1  myocyte-specific enhancer factor 2C isoform 1

    See identical proteins and their annotated locations for NP_001180279.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 6, and 9-11 all encode the same isoform (1).
    Source sequence(s)
    AC008525, AL833268, BC026341, DC377336, DC377710, L08895
    Consensus CDS
    CCDS47245.1
    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL7
    Related
    ENSP00000396219.2, OTTHUMP00000222410, ENST00000437473.6, OTTHUMT00000369817
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  6. NM_001308002.2NP_001294931.1  myocyte-specific enhancer factor 2C isoform 6

    See identical proteins and their annotated locations for NP_001294931.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (6) is shorter than isoform 1. Variants 7 and 13 both encode the same isoform (6).
    Source sequence(s)
    AC008525, AC008835
    Consensus CDS
    CCDS78034.1
    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL6
    Related
    ENSP00000486554.1, OTTHUMP00000222413, ENST00000629612.2
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. NM_001363581.1NP_001350510.1  myocyte-specific enhancer factor 2C isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, the 3' UTR, and the 3' coding sequence compared to variant 1. The resulting isoform (7) has a shorter and distinct C-terminus compared to isoform 1. Variants 8 and 14-17 all encode the same isoform (7).
    Source sequence(s)
    AC008525, AC008835
    Consensus CDS
    CCDS87313.1
  8. NM_001364329.1NP_001351258.1  myocyte-specific enhancer factor 2C isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 1, 6, 10, and 11, encodes isoform 1.
    Source sequence(s)
    AC008525, AC008835
  9. NM_001364330.1NP_001351259.1  myocyte-specific enhancer factor 2C isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 1, 6, 9, and 11, encodes isoform 1.
    Source sequence(s)
    AC008525, AC008835
  10. NM_001364331.1NP_001351260.1  myocyte-specific enhancer factor 2C isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 1, 6, 9, and 10, encodes isoform 1.
    Source sequence(s)
    AC008525, AC008835
  11. NM_001364332.1NP_001351261.1  myocyte-specific enhancer factor 2C isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variant 5, encodes isoform 5.
    Source sequence(s)
    AC008525, AC008835
  12. NM_001364333.1NP_001351262.1  myocyte-specific enhancer factor 2C isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variant 7, encodes isoform 6.
    Source sequence(s)
    AC008525, AC008835
  13. NM_001364334.1NP_001351263.1  myocyte-specific enhancer factor 2C isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 8, 15, 16, and 17, encodes isoform 7.
    Source sequence(s)
    AC008525, AC008835
  14. NM_001364335.1NP_001351264.1  myocyte-specific enhancer factor 2C isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 8, 14, 16, and 17, encodes isoform 7.
    Source sequence(s)
    AC008525, AC008835
  15. NM_001364336.1NP_001351265.1  myocyte-specific enhancer factor 2C isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 8, 14, 15, and 17, encodes isoform 7.
    Source sequence(s)
    AC008525, AC008835
  16. NM_001364337.1NP_001351266.1  myocyte-specific enhancer factor 2C isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 8, 14, 15, and 16, encodes isoform 7.
    Source sequence(s)
    AC008525, AC008835
  17. NM_001364338.1NP_001351267.1  myocyte-specific enhancer factor 2C isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC008525, AC008835
  18. NM_001364339.1NP_001351268.1  myocyte-specific enhancer factor 2C isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 20, 21, and 22, encodes isoform 9.
    Source sequence(s)
    AC008525, AC008835
  19. NM_001364340.1NP_001351269.1  myocyte-specific enhancer factor 2C isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 19, 21, and 22, encodes isoform 9.
    Source sequence(s)
    AC008525, AC008835
  20. NM_001364341.1NP_001351270.1  myocyte-specific enhancer factor 2C isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 19, 20, and 22, encodes isoform 9.
    Source sequence(s)
    AC008525, AC008835
  21. NM_001364342.1NP_001351271.1  myocyte-specific enhancer factor 2C isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 19, 20, and 21, encodes isoform 9.
    Source sequence(s)
    AC008525, AC008835
  22. NM_001364343.1NP_001351272.1  myocyte-specific enhancer factor 2C isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC008525, AC008835
  23. NM_001364344.1NP_001351273.1  myocyte-specific enhancer factor 2C isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC008525, AC008835
  24. NM_001364345.1NP_001351274.1  myocyte-specific enhancer factor 2C isoform 12

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variants 26 and 27, encodes isoform 12.
    Source sequence(s)
    AC008525, AC008835
  25. NM_001364346.1NP_001351275.1  myocyte-specific enhancer factor 2C isoform 12

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 25 and 27, encodes isoform 12.
    Source sequence(s)
    AC008525, AC008835
  26. NM_001364347.1NP_001351276.1  myocyte-specific enhancer factor 2C isoform 12

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variants 25 and 26, encodes isoform 12.
    Source sequence(s)
    AC008525, AC008835
  27. NM_001364348.1NP_001351277.1  myocyte-specific enhancer factor 2C isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variants 29 and 30, encodes isoform 13.
    Source sequence(s)
    AC008525, AC008835
  28. NM_001364349.1NP_001351278.1  myocyte-specific enhancer factor 2C isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29), as well as variants 28 and 30, encodes isoform 13.
    Source sequence(s)
    AC008525, AC008835
  29. NM_001364350.1NP_001351279.1  myocyte-specific enhancer factor 2C isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30), as well as variants 28 and 29, encodes isoform 13.
    Source sequence(s)
    AC008525, AC008835
  30. NM_001364352.1NP_001351281.1  myocyte-specific enhancer factor 2C isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC008525, AC008835
  31. NM_001364353.1NP_001351282.1  myocyte-specific enhancer factor 2C isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC008525
  32. NM_001364354.1NP_001351283.1  myocyte-specific enhancer factor 2C isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33), as well as variant 34, encodes isoform 16.
    Source sequence(s)
    AC008525, AC008835
  33. NM_001364355.1NP_001351284.1  myocyte-specific enhancer factor 2C isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (34), as well as variant 33, encodes isoform 16.
    Source sequence(s)
    AC008525, AC008835
  34. NM_001364356.1NP_001351285.1  myocyte-specific enhancer factor 2C isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC008525
  35. NM_001364357.1NP_001351286.1  myocyte-specific enhancer factor 2C isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC008525
  36. NM_002397.4NP_002388.2  myocyte-specific enhancer factor 2C isoform 1

    See identical proteins and their annotated locations for NP_002388.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1. Variants 1, 6, and 9-11 all encode the same isoform (1).
    Source sequence(s)
    AC008525, AL833268, DC377336, DC377710, L08895
    Consensus CDS
    CCDS47245.1
    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL7
    Related
    ENSP00000421925.4, OTTHUMP00000222409, ENST00000504921.6, OTTHUMT00000369815
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p12 Primary Assembly

    Range
    88718241..88904105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009480.1XP_016864969.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/Swiss-Prot
    Q06413
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  2. XM_017009481.2XP_016864970.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000426665.2, OTTHUMP00000278382, ENST00000514028.5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  3. XM_011543401.1XP_011541703.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0R4J2G5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  4. XM_017009477.1XP_016864966.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL6
    Related
    ENSP00000423597.2, OTTHUMP00000222544, ENST00000508569.5, OTTHUMT00000370094
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  5. XM_011543400.1XP_011541702.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000424606.1, OTTHUMP00000222543, ENST00000514015.5, OTTHUMT00000370093
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  6. XM_017009483.2XP_016864972.1  myocyte-specific enhancer factor 2C isoform X7

    UniProtKB/TrEMBL
    A0A0D9SFD0
    Related
    ENSP00000486490.1, OTTHUMP00000278379, ENST00000627659.2
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. XM_017009478.2XP_016864967.1  myocyte-specific enhancer factor 2C isoform X4

    UniProtKB/Swiss-Prot
    Q06413
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  8. XM_006714625.4XP_006714688.1  myocyte-specific enhancer factor 2C isoform X9

    See identical proteins and their annotated locations for XP_006714688.1

    UniProtKB/Swiss-Prot
    Q06413
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:117171
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  9. XM_017009482.2XP_016864971.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0R4J2G5
    Related
    ENSP00000422390.2, OTTHUMP00000222542, ENST00000510942.5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  10. XM_017009476.2XP_016864965.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL6
    Related
    ENSP00000490354.1, OTTHUMP00000282749, ENST00000637481.1
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  11. XM_017009479.2XP_016864968.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/Swiss-Prot
    Q06413
    Related
    ENSP00000490630.1, OTTHUMP00000282750, ENST00000636998.1
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  12. XM_024446061.1XP_024301829.1  myocyte-specific enhancer factor 2C isoform X6

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  13. XM_024446062.1XP_024301830.1  myocyte-specific enhancer factor 2C isoform X8

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  14. XM_024446060.1XP_024301828.1  myocyte-specific enhancer factor 2C isoform X5

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  15. XM_006714619.3XP_006714682.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL7
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  16. XM_005248511.3XP_005248568.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_005248568.1

    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL7
    Related
    OTTHUMP00000282752
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  17. XM_024446057.1XP_024301825.1  myocyte-specific enhancer factor 2C isoform X2

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  18. XM_011543397.3XP_011541699.1  myocyte-specific enhancer factor 2C isoform X2

    See identical proteins and their annotated locations for XP_011541699.1

    UniProtKB/TrEMBL
    A0A0D9SGI5
    Related
    OTTHUMP00000278381
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  19. XM_017009475.2XP_016864964.1  myocyte-specific enhancer factor 2C isoform X2

    UniProtKB/TrEMBL
    A0A0D9SGI5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  20. XM_024446054.1XP_024301822.1  myocyte-specific enhancer factor 2C isoform X1

    Related
    ENSP00000425636.1, ENST00000506554.5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  21. XM_024446055.1XP_024301823.1  myocyte-specific enhancer factor 2C isoform X1

    Related
    ENSP00000490473.1, ENST00000636294.1
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  22. XM_024446058.1XP_024301826.1  myocyte-specific enhancer factor 2C isoform X2

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  23. XM_024446059.1XP_024301827.1  myocyte-specific enhancer factor 2C isoform X2

    Related
    ENSP00000487538.1, ENST00000625585.2
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97151
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  24. XM_024446056.1XP_024301824.1  myocyte-specific enhancer factor 2C isoform X1

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  25. XM_011543396.3XP_011541698.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_011541698.1

    UniProtKB/Swiss-Prot
    Q06413
    UniProtKB/TrEMBL
    A0A024RAL7
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  26. XM_024446053.1XP_024301821.1  myocyte-specific enhancer factor 2C isoform X1

    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:107153
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
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