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Mef2c myocyte enhancer factor 2C [ Mus musculus (house mouse) ]

Gene ID: 17260, updated on 19-Feb-2024

Summary

Official Symbol
Mef2cprovided by MGI
Official Full Name
myocyte enhancer factor 2Cprovided by MGI
Primary source
MGI:MGI:99458
See related
Ensembl:ENSMUSG00000005583 AllianceGenome:MGI:99458
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mef2; 5430401D19Rik; 9930028G15Rik
Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and histone deacetylase binding activity. Involved in several processes, including animal organ development; modulation of chemical synaptic transmission; and positive regulation of cell differentiation. Acts upstream of or within several processes, including animal organ development; cardiac muscle hypertrophy in response to stress; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and urinary system. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 49.3), frontal lobe adult (RPKM 37.4) and 11 other tissues See more
Orthologs
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Genomic context

See Mef2c in Genome Data Viewer
Location:
13 C3; 13 43.68 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (83652136..83815197)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (83504017..83667079)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35149 Neighboring gene predicted gene, 33217 Neighboring gene predicted gene, 33274 Neighboring gene STARR-positive B cell enhancer ABC_E5408 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83664236-83664536 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83666025-83666326 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83678903-83679204 Neighboring gene STARR-positive B cell enhancer ABC_E8895 Neighboring gene VISTA enhancer mm1175 Neighboring gene STARR-positive B cell enhancer ABC_E747 Neighboring gene predicted gene, 26803 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83788426-83788726 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83789544-83789845 Neighboring gene STARR-positive B cell enhancer mm9_chr13:83790286-83790587 Neighboring gene STARR-positive B cell enhancer ABC_E10805 Neighboring gene STARR-seq mESC enhancer starr_35152 Neighboring gene STARR-seq mESC enhancer starr_35153 Neighboring gene Mir9-2 host gene Neighboring gene microRNA 9b-2 Neighboring gene microRNA 9-2 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables HMG box domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone deacetylase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables minor groove of adenine-thymine-rich DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in B cell homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in B cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in MAPK cascade IDA
Inferred from Direct Assay
more info
PubMed 
involved_in MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within blood vessel remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cardiac muscle cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cardiac muscle cell differentiation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within cardiac muscle hypertrophy in response to stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cardiac ventricle formation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cardiac ventricle formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cartilage morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell morphogenesis involved in neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of cell proliferation in bone marrow IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cellular response to calcium ion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to fluid shear stress IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to lipopolysaccharide IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to parathyroid hormone stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to transforming growth factor beta stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to trichostatin A IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within chondrocyte differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in embryonic heart tube development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in embryonic heart tube development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within endochondral ossification IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within endochondral ossification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell proliferation involved in renal tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in excitatory postsynaptic potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in germinal center formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in glomerulus morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart looping IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in humoral immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in learning or memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in melanocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within monocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within muscle cell fate determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of ossification ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of vascular associated smooth muscle cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of vascular associated smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of vascular endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in nephron tubule epithelial cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in neural crest cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in osteoblast differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within osteoblast differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within outflow tract morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in platelet formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of alkaline phosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of behavioral fear response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of bone mineralization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cardiac muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cardiac muscle cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cardiac muscle hypertrophy ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of cell proliferation in bone marrow IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of macrophage apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of myoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of osteoblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in primary heart field specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of AMPA receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of NMDA receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of dendritic spine development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of germinal center formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of megakaryocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of sarcomere organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synaptic activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synaptic plasticity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in renal tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to ischemia ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within roof of mouth development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in secondary heart field specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sinoatrial valve morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within skeletal muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in skeletal muscle cell differentiation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within skeletal muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within smooth muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sympathetic neuron axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transdifferentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in ventricular cardiac muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in sarcomere ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
myocyte-specific enhancer factor 2C

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170537.2NP_001164008.1  myocyte-specific enhancer factor 2C isoform 1

    See identical proteins and their annotated locations for NP_001164008.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region, compared to variant 3, resulting in an isoform (1) that is shorter than isoform 3.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS49320.1
    UniProtKB/TrEMBL
    A0A0G2JDT0, Q3V1B5
    Related
    ENSMUSP00000143315.2, ENSMUST00000199450.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  2. NM_001347564.2NP_001334493.1  myocyte-specific enhancer factor 2C isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Variants 3, 4 and 5 all encode isoform 3.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS84042.1
    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  3. NM_001347566.2NP_001334495.1  myocyte-specific enhancer factor 2C isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84042.1
    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Related
    ENSMUSP00000143401.2, ENSMUST00000199019.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  4. NM_001347567.2NP_001334496.1  myocyte-specific enhancer factor 2C isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. Variants 3, 4 and 5 all encode isoform 3.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84042.1
    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Related
    ENSMUSP00000143212.2, ENSMUST00000199105.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  5. NM_001347568.2NP_001334497.1  myocyte-specific enhancer factor 2C isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84045.1
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  6. NM_001347569.2NP_001334498.1  myocyte-specific enhancer factor 2C isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (4) is shorter than isoform 3. Both variants 6 and 7 encode isoform 4.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84045.1
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Related
    ENSMUSP00000138826.3, ENSMUST00000185052.6
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. NM_001347571.2NP_001334500.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  8. NM_001347572.2NP_001334501.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  9. NM_001347573.2NP_001334502.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Related
    ENSMUSP00000142595.2, ENSMUST00000199210.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  10. NM_001347574.2NP_001334503.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  11. NM_001347575.2NP_001334504.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  12. NM_001347576.2NP_001334505.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Related
    ENSMUSP00000143420.2, ENSMUST00000197681.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  13. NM_001347577.2NP_001334506.1  myocyte-specific enhancer factor 2C isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3, resulting in an isoform (5) that is shorter than isoform 3. Variants 8 through 14 all encode isoform 5.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84043.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Related
    ENSMUSP00000143227.2, ENSMUST00000197146.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  14. NM_001347578.2NP_001334507.1  myocyte-specific enhancer factor 2C isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (6) is shorter than isoform 3.
    Source sequence(s)
    CT025631, CU074400
    Consensus CDS
    CCDS84044.1
    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Related
    ENSMUSP00000142714.2, ENSMUST00000199432.5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  15. NM_001347579.2NP_001334508.1  myocyte-specific enhancer factor 2C isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.
    Source sequence(s)
    AC107750, CT025631, CU074400
    UniProtKB/TrEMBL
    A0A0G2JDQ1
  16. NM_001347580.2NP_001334509.1  myocyte-specific enhancer factor 2C isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17) differs in the 5' UTR, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (7) has a distinct C-terminus and is shorter than isoform 3. Both variants 16 and 17 encode isoform 7.
    Source sequence(s)
    CT025631, CU074400
    UniProtKB/TrEMBL
    A0A0G2JDQ1
    Related
    ENSMUSP00000142456.2, ENSMUST00000197722.5
  17. NM_001347581.2NP_001334510.1  myocyte-specific enhancer factor 2C isoform 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18) differs in the 5' UTR, lacks an in-frame exon in the central coding region, and uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 3. The encoded isoform (8) has a distinct C-terminus and is shorter than isoform 3.
    Source sequence(s)
    CT025631, CU074400
    UniProtKB/TrEMBL
    A0A0G2JDQ1
  18. NM_025282.4NP_079558.1  myocyte-specific enhancer factor 2C isoform 2

    See identical proteins and their annotated locations for NP_079558.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate in-frame exon in the 5' coding region, lacks an in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3.
    Source sequence(s)
    AC107750, CT025631, CU074400
    Consensus CDS
    CCDS26664.1
    UniProtKB/TrEMBL
    A0A0G2JE18
    Related
    ENSMUSP00000143742.2, ENSMUST00000198199.5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    83652136..83815197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517123.4XP_006517186.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006517186.1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  2. XM_036157888.1XP_036013781.1  myocyte-specific enhancer factor 2C isoform X4

    UniProtKB/TrEMBL
    A0A0G2JDT0, A0A0H2UKB6
    Related
    ENSMUSP00000005722.9, ENSMUST00000005722.14
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  3. XM_036157891.1XP_036013784.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  4. XM_036157892.1XP_036013785.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  5. XM_030247172.2XP_030103032.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  6. XM_036157887.1XP_036013780.1  myocyte-specific enhancer factor 2C isoform X2

    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  7. XM_017315405.3XP_017170894.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  8. XM_036157895.1XP_036013788.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  9. XM_030247175.2XP_030103035.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/TrEMBL
    A0A0G2JDT0, Q3V1B5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  10. XM_011244492.4XP_011242794.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_011242794.1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  11. XM_030247177.2XP_030103037.1  myocyte-specific enhancer factor 2C isoform X8

    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  12. XM_030247176.2XP_030103036.1  myocyte-specific enhancer factor 2C isoform X3

    UniProtKB/TrEMBL
    A0A0G2JDT0, Q3V1B5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  13. XM_006517127.5XP_006517190.1  myocyte-specific enhancer factor 2C isoform X3

    See identical proteins and their annotated locations for XP_006517190.1

    UniProtKB/TrEMBL
    A0A0G2JDT0, Q3V1B5
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  14. XM_011244495.4XP_011242797.1  myocyte-specific enhancer factor 2C isoform X9

    UniProtKB/TrEMBL
    A0A0G2JDT0, A0A0H2UH28
    Related
    ENSMUSP00000132547.3, ENSMUST00000163888.8
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:116170
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  15. XM_006517126.4XP_006517189.1  myocyte-specific enhancer factor 2C isoform X2

    See identical proteins and their annotated locations for XP_006517189.1

    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  16. XM_036157889.1XP_036013782.1  myocyte-specific enhancer factor 2C isoform X5

    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  17. XM_006517128.5XP_006517191.1  myocyte-specific enhancer factor 2C isoform X4

    UniProtKB/TrEMBL
    A0A0G2JDT0, A0A0H2UKB6
    Related
    ENSMUSP00000142487.2, ENSMUST00000198217.5
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  18. XM_006517130.4XP_006517193.1  myocyte-specific enhancer factor 2C isoform X6

    See identical proteins and their annotated locations for XP_006517193.1

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  19. XM_006517132.5XP_006517195.1  myocyte-specific enhancer factor 2C isoform X7

    See identical proteins and their annotated locations for XP_006517195.1

    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:96150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
  20. XM_006517124.5XP_006517187.1  myocyte-specific enhancer factor 2C isoform X1

    See identical proteins and their annotated locations for XP_006517187.1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  21. XM_036157893.1XP_036013786.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  22. XM_036157890.1XP_036013783.1  myocyte-specific enhancer factor 2C isoform X8

    UniProtKB/TrEMBL
    A0A0G2JE18
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  23. XM_036157894.1XP_036013787.1  myocyte-specific enhancer factor 2C isoform X6

    UniProtKB/TrEMBL
    A0A0G2JE18, A0A0G2JEC2
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
  24. XM_036157886.1XP_036013779.1  myocyte-specific enhancer factor 2C isoform X1

    UniProtKB/Swiss-Prot
    Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20
    UniProtKB/TrEMBL
    A0A0G2JDT0
    Conserved Domains (2) summary
    COG5068
    Location:1245
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:278
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...