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MEF2A myocyte enhancer factor 2A [ Homo sapiens (human) ]

Gene ID: 4205, updated on 6-Jul-2026
Official Symbol
MEF2Aprovided by HGNC
Official Full Name
myocyte enhancer factor 2Aprovided by HGNC
Primary source
HGNC:HGNC:6993
See related
Ensembl:ENSG00000068305 MIM:600660; AllianceGenome:HGNC:6993
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mef2; ADCAD1; RSRFC4; RSRFC9
Summary
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Expression
Ubiquitous expression in heart (RPKM 14.6), brain (RPKM 12.2) and 25 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MEF2A in Genome Data Viewer
Location:
15q26.3
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (99565417..99716488)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (97329154..97480250)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (100105622..100256693)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371019 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10155 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10156 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10157 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10158 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10159 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6869 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10160 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:100105511-100106486 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:100106487-100107460 Neighboring gene ribosomal protein L7 pseudogene 5 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:100119332-100119832 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:100119833-100120333 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10161 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:100169236-100169886 Neighboring gene MPRA-validated peak2449 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6872 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10162 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10163 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:100266134-100266634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:100266635-100267135 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6873 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6874 Neighboring gene LysM domain containing 4 Neighboring gene MPRA-validated peak2450 silencer Neighboring gene uncharacterized LOC105371020 Neighboring gene RNA, 7SL, cytoplasmic 484, pseudogene Neighboring gene dynamin 1 pseudogene 46

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Myocyte enhancing factor-2A in Alzheimer's disease: genetic analysis and association with MEF2A-polymorphisms. González P, et al. Neurosci Lett, 2007 Jan 3. PMID 17112666
  2. Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface. Wei J, et al. JCI Insight, 2017 Sep 7. PMID 28878124, Free PMC Article
  3. Transcription factor MEF2A mutations in patients with coronary artery disease. Bhagavatula MR, et al. Hum Mol Genet, 2004 Dec 15. PMID 15496429, Free PMC Article
  4. Novel 6-bp deletion in MEF2A linked to premature coronary artery disease in a large Chinese family. Xu DL, et al. Mol Med Rep, 2016 Jul. PMID 27221044, Free PMC Article
  5. MEF2A sequence variants and coronary artery disease: a change of heart? Altshuler D, et al. J Clin Invest, 2005 Apr. PMID 15841171, Free PMC Article

See all (176) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MEF2A is a transcription factor for circPVT1 and contributes to the malignancy of acute myeloid leukemia.
    Title: MEF2A is a transcription factor for circPVT1 and contributes to the malignancy of acute myeloid leukemia.
  2. The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment.
    Title: The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment.
  3. Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation.
    Title: Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation.
  4. Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.
    Title: Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.
  5. A Study of transcription factor MEF2A gene polymorphisms in patients with coronary artery disease.
    Title: A Study of transcription factor MEF2A gene polymorphisms in patients with coronary artery disease.
  6. Association between MEF2 family gene polymorphisms and susceptibility to multiple sclerosis in Chinese population.
    Title: Association between MEF2 family gene polymorphisms and susceptibility to multiple sclerosis in Chinese population.
  7. HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.
    Title: HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.
  8. MiRNA-615-3p Alleviates Oxidative Stress Injury of Human Cardiomyocytes Via PI3K/Akt Signaling by Targeting MEF2A.
    Title: MiRNA-615-3p Alleviates Oxidative Stress Injury of Human Cardiomyocytes Via PI3K/Akt Signaling by Targeting MEF2A.
  9. Detection and functional characterization of a novel MEF2A variation responsible for familial dilated cardiomyopathy.
    Title: Detection and functional characterization of a novel MEF2A variation responsible for familial dilated cardiomyopathy.
  10. MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression.
    Title: MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression.
Submit: New GeneRIF Correction See all GeneRIFs (87)

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Coronary artery disease, autosomal dominant, 1
MedGen: C1842247 OMIM: 608320 GeneReviews: Not available
Compare labs

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Protein interactions

Protein Gene Interaction Pubs
Tat tat Phosphorylated DING (pDING) inhibits HIV-1 Tat-induced neuronal cell injury by suppressing the activity of serine/threonine kinases p38 MAPK and Cdk5 and enhancing the activity of neuroprotective factor MEF2 through the phosphotase activity of pDING PubMed
tat HIV-1 Tat increases levels of phosphorylated MEF2 in human neuronal cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
  
enables DNA-binding transcription factor binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables SMAD binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
  
enables histone acetyltransferase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
  
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to calcium ion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in dendrite morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in heart development IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in muscle cell development IEA
Inferred from Electronic Annotation
more info
  
involved_in muscle cell development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in muscle organ development NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of cardiac muscle hypertrophy IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of cardiac muscle hypertrophy IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromatin IEA
Inferred from Electronic Annotation
more info
  
located_in chromatin ISA
Inferred from Sequence Alignment
more info
  
located_in chromatin ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
myocyte-specific enhancer factor 2A
Names
MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
serum response factor-like protein 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016443.2 RefSeqGene

    Range
    5057..155561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001130926.5 → NP_001124398.1  myocyte-specific enhancer factor 2A isoform 2

    See identical proteins and their annotated locations for NP_001124398.1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000509537.1, ENST00000691492.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  2. NM_001130927.5 → NP_001124399.1  myocyte-specific enhancer factor 2A isoform 3

    See identical proteins and their annotated locations for NP_001124399.1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45363.1
    UniProtKB/TrEMBL
    A8K720
    Related
    ENSP00000454120.1, ENST00000558812.5
    Conserved Domains (2) summary
    pfam12347
    Location:29 → 82
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
    cl00109
    Location:2 → 25
    MADS; MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ ...

  3. NM_001130928.4 → NP_001124400.1  myocyte-specific enhancer factor 2A isoform 4

    See identical proteins and their annotated locations for NP_001124400.1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS58401.1
    UniProtKB/TrEMBL
    A0A0S2Z4C8, A8K720
    Related
    ENSP00000399460.2, ENST00000449277.6
    Conserved Domains (2) summary
    pfam12347
    Location:29 → 81
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
    cl00109
    Location:2 → 25
    MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

  4. NM_001171894.5 → NP_001165365.1  myocyte-specific enhancer factor 2A isoform 2

    See identical proteins and their annotated locations for NP_001165365.1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559204.1, ENST00000889145.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  5. NM_001319206.4 → NP_001306135.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000453095.1, ENST00000557942.6
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  6. NM_001352614.4 → NP_001339543.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000617053.1, ENST00000946994.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  7. NM_001352615.4 → NP_001339544.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  8. NM_001352616.4 → NP_001339545.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559195.1, ENST00000889136.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  9. NM_001352617.4 → NP_001339546.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  10. NM_001352618.4 → NP_001339547.1  myocyte-specific enhancer factor 2A isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7
    Related
    ENSP00000559197.1, ENST00000889138.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  11. NM_001365201.3 → NP_001352130.1  myocyte-specific enhancer factor 2A isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92068.1
    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Related
    ENSP00000337202.8, ENST00000338042.11
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  12. NM_001365202.3 → NP_001352131.1  myocyte-specific enhancer factor 2A isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92068.1
    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Related
    ENSP00000509700.1, ENST00000690055.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  13. NM_001365203.3 → NP_001352132.1  myocyte-specific enhancer factor 2A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92067.1
    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000509137.1, ENST00000686611.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  14. NM_001365204.3 → NP_001352133.1  myocyte-specific enhancer factor 2A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92067.1
    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000559194.1, ENST00000889135.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  15. NM_001365205.3 → NP_001352134.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559188.1, ENST00000889129.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  16. NM_001365206.3 → NP_001352135.1  myocyte-specific enhancer factor 2A isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7
    Related
    ENSP00000559209.1, ENST00000889150.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  17. NM_001365207.3 → NP_001352136.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559187.1, ENST00000889128.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  18. NM_001365208.3 → NP_001352137.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000453441.1, ENST00000557785.5
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  19. NM_001365209.3 → NP_001352138.1  myocyte-specific enhancer factor 2A isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45363.1
    UniProtKB/TrEMBL
    A8K720
    Related
    ENSP00000559205.1, ENST00000889146.1
    Conserved Domains (2) summary
    pfam12347
    Location:29 → 82
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
    cl00109
    Location:2 → 25
    MADS; MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ ...

  20. NM_001365210.2 → NP_001352139.1  myocyte-specific enhancer factor 2A isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  21. NM_001365211.2 → NP_001352140.1  myocyte-specific enhancer factor 2A isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 150
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  22. NM_001393558.2 → NP_001380487.1  myocyte-specific enhancer factor 2A isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8SDA8, A0ACI8UIC7
    Related
    ENSP00000559192.1, ENST00000889133.1
    Conserved Domains (1) summary
    pfam12347
    Location:29 → 83
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  23. NM_001393559.2 → NP_001380488.1  myocyte-specific enhancer factor 2A isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS58401.1
    UniProtKB/TrEMBL
    A0A0S2Z4C8, A8K720
    Related
    ENSP00000559206.1, ENST00000889147.1
    Conserved Domains (2) summary
    pfam12347
    Location:29 → 81
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
    cl00109
    Location:2 → 25
    MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

  24. NM_001393560.2 → NP_001380489.1  myocyte-specific enhancer factor 2A isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8R2V7, A0ACI8UEJ3
    Related
    ENSP00000617048.1, ENST00000946989.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 309
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  25. NM_001393561.3 → NP_001380490.1  myocyte-specific enhancer factor 2A isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8QSY8
    Related
    ENSP00000617049.1, ENST00000946990.1
    Conserved Domains (1) summary
    cl00109
    Location:2 → 20
    MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...

  26. NM_001400028.1 → NP_001386957.1  myocyte-specific enhancer factor 2A isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8UHK8
    Related
    ENSP00000617066.1, ENST00000947007.1

  27. NM_001400029.1 → NP_001386958.1  myocyte-specific enhancer factor 2A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92067.1
    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000617060.1, ENST00000947001.1

  28. NM_001400030.1 → NP_001386959.1  myocyte-specific enhancer factor 2A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS92067.1
    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3

  29. NM_001400031.1 → NP_001386960.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559212.1, ENST00000889153.1

  30. NM_001400032.1 → NP_001386961.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559220.1, ENST00000889161.1

  31. NM_001400033.1 → NP_001386962.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720

  32. NM_001400034.1 → NP_001386963.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000617061.1, ENST00000947002.1

  33. NM_001400035.1 → NP_001386964.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559198.1, ENST00000889139.1

  34. NM_001400036.1 → NP_001386965.1  myocyte-specific enhancer factor 2A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS81920.1
    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000559186.1, ENST00000889127.1

  35. NM_001400037.1 → NP_001386966.1  myocyte-specific enhancer factor 2A isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7

  36. NM_001400038.1 → NP_001386967.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7

  37. NM_001400039.1 → NP_001386968.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559183.1, ENST00000889124.1

  38. NM_001400040.1 → NP_001386969.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000617074.1, ENST00000947015.1

  39. NM_001400049.1 → NP_001386978.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7

  40. NM_001400050.1 → NP_001386979.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559191.1, ENST00000889132.1

  41. NM_001400051.1 → NP_001386980.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559207.1, ENST00000889148.1

  42. NM_001400052.1 → NP_001386981.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559219.1, ENST00000889160.1

  43. NM_001400053.1 → NP_001386982.1  myocyte-specific enhancer factor 2A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559214.1, ENST00000889155.1

  44. NM_001400054.1 → NP_001386983.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  45. NM_001400055.1 → NP_001386984.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559185.1, ENST00000889126.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  46. NM_001400056.1 → NP_001386985.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000617081.1, ENST00000947022.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  47. NM_001400057.1 → NP_001386986.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  48. NM_001400058.1 → NP_001386987.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559189.1, ENST00000889130.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  49. NM_001400059.1 → NP_001386988.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000598394.1, ENST00000928335.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  50. NM_001400060.1 → NP_001386989.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559217.1, ENST00000889158.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  51. NM_001400061.1 → NP_001386990.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559200.1, ENST00000889141.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  52. NM_001400062.1 → NP_001386991.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000617076.1, ENST00000947017.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  53. NM_001400063.1 → NP_001386992.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  54. NM_001400064.1 → NP_001386993.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  55. NM_001400065.1 → NP_001386994.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  56. NM_001400066.1 → NP_001386995.1  myocyte-specific enhancer factor 2A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS53978.1
    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000559193.1, ENST00000889134.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  57. NM_001400067.1 → NP_001386996.1  myocyte-specific enhancer factor 2A isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8UEI0, A0ACI8UIC7
    Related
    ENSP00000617041.1, ENST00000946982.1

  58. NM_001400068.1 → NP_001386997.1  myocyte-specific enhancer factor 2A isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    UniProtKB/TrEMBL
    A0ACI8SDA8, A0ACI8UIC7
    Related
    ENSP00000559190.1, ENST00000889131.1

  59. NM_001400069.1 → NP_001386998.1  myocyte-specific enhancer factor 2A isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967

  60. NM_001400070.1 → NP_001386999.1  myocyte-specific enhancer factor 2A isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967

  61. NM_001400071.1 → NP_001387000.1  myocyte-specific enhancer factor 2A isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967

  62. NM_005587.6 → NP_005578.2  myocyte-specific enhancer factor 2A isoform 1

    See identical proteins and their annotated locations for NP_005578.2

    Status: REVIEWED

    Source sequence(s)
    AC022692, AC103967
    Consensus CDS
    CCDS45362.1
    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000346389.5, ENST00000354410.9
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    99565417..99716488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011521572.3 → XP_011519874.1  myocyte-specific enhancer factor 2A isoform X1

    See identical proteins and their annotated locations for XP_011519874.1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  2. XM_011521579.3 → XP_011519881.1  myocyte-specific enhancer factor 2A isoform X1

    See identical proteins and their annotated locations for XP_011519881.1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Related
    ENSP00000617038.1, ENST00000946979.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  3. XM_047432530.1 → XP_047288486.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  4. XM_047432531.1 → XP_047288487.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  5. XM_047432528.1 → XP_047288484.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7

  6. XM_011521582.3 → XP_011519884.1  myocyte-specific enhancer factor 2A isoform X2

    See identical proteins and their annotated locations for XP_011519884.1

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000617046.1, ENST00000946987.1
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 152
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  7. XM_047432520.1 → XP_047288476.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  8. XM_047432523.1 → XP_047288479.1  myocyte-specific enhancer factor 2A isoform X4

    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7

  9. XM_047432521.1 → XP_047288477.1  myocyte-specific enhancer factor 2A isoform X2

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000617057.1, ENST00000946998.1

  10. XM_047432529.1 → XP_047288485.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000617063.1, ENST00000947004.1

  11. XM_011521585.3 → XP_011519887.1  myocyte-specific enhancer factor 2A isoform X7

    UniProtKB/TrEMBL
    A0ACI8UGD6, A0ACI8UIC7
    Related
    ENSP00000617058.1, ENST00000946999.1
    Conserved Domains (2) summary
    pfam12347
    Location:30 → 88
    HJURP_C; Holliday junction regulator protein family C-terminal repeat
    cl00109
    Location:2 → 18
    MADS; MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ ...

  12. XM_047432532.1 → XP_047288488.1  myocyte-specific enhancer factor 2A isoform X8

    UniProtKB/TrEMBL
    A0ACI8UEI0, A0ACI8UIC7
    Related
    ENSP00000559196.1, ENST00000889137.1

  13. XM_011521573.3 → XP_011519875.1  myocyte-specific enhancer factor 2A isoform X1

    See identical proteins and their annotated locations for XP_011519875.1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  14. XM_047432527.1 → XP_047288483.1  myocyte-specific enhancer factor 2A isoform X4

    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7

  15. XM_047432519.1 → XP_047288475.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  16. XM_047432526.1 → XP_047288482.1  myocyte-specific enhancer factor 2A isoform X2

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3
    Related
    ENSP00000559218.1, ENST00000889159.1

  17. XM_047432522.1 → XP_047288478.1  myocyte-specific enhancer factor 2A isoform X3

    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720
    Related
    ENSP00000617047.1, ENST00000946988.1

  18. XM_047432525.1 → XP_047288481.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720
    Related
    ENSP00000617086.1, ENST00000947027.1
    Conserved Domains (2) summary
    COG5068
    Location:1 → 235
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

  19. XM_011521577.3 → XP_011519879.1  myocyte-specific enhancer factor 2A isoform X1

    See identical proteins and their annotated locations for XP_011519879.1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3
    Conserved Domains (2) summary
    cd00265
    Location:2 → 78
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam12347
    Location:97 → 156
    HJURP_C; Holliday junction regulator protein family C-terminal repeat

  20. XM_047432524.1 → XP_047288480.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
    Related
    ENSP00000559221.1, ENST00000889162.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    97329154..97480250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054377935.1 → XP_054233910.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  2. XM_054377938.1 → XP_054233913.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  3. XM_054377951.1 → XP_054233926.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720

  4. XM_054377952.1 → XP_054233927.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720

  5. XM_054377949.1 → XP_054233924.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7

  6. XM_054377941.1 → XP_054233916.1  myocyte-specific enhancer factor 2A isoform X2

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3

  7. XM_054377940.1 → XP_054233915.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  8. XM_054377944.1 → XP_054233919.1  myocyte-specific enhancer factor 2A isoform X4

    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7

  9. XM_054377942.1 → XP_054233917.1  myocyte-specific enhancer factor 2A isoform X2

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3

  10. XM_054377950.1 → XP_054233925.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7

  11. XM_054377953.1 → XP_054233928.1  myocyte-specific enhancer factor 2A isoform X7

    UniProtKB/TrEMBL
    A0ACI8UGD6, A0ACI8UIC7

  12. XM_054377954.1 → XP_054233929.1  myocyte-specific enhancer factor 2A isoform X8

    UniProtKB/TrEMBL
    A0ACI8UEI0, A0ACI8UIC7

  13. XM_054377936.1 → XP_054233911.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  14. XM_054377948.1 → XP_054233923.1  myocyte-specific enhancer factor 2A isoform X4

    UniProtKB/TrEMBL
    A0ACI8RAR3, A0ACI8UIC7

  15. XM_054377939.1 → XP_054233914.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  16. XM_054377947.1 → XP_054233922.1  myocyte-specific enhancer factor 2A isoform X2

    UniProtKB/Swiss-Prot
    B4DFQ7, F6XG23, O43814, Q02078, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
    UniProtKB/TrEMBL
    A0A0S2Z453, A0ACI8UIC3

  17. XM_054377943.1 → XP_054233918.1  myocyte-specific enhancer factor 2A isoform X3

    UniProtKB/TrEMBL
    A0A0S2Z4N0, A8K720

  18. XM_054377946.1 → XP_054233921.1  myocyte-specific enhancer factor 2A isoform X6

    UniProtKB/TrEMBL
    A0A0S2Z417, A8K720

  19. XM_054377937.1 → XP_054233912.1  myocyte-specific enhancer factor 2A isoform X1

    UniProtKB/TrEMBL
    A0A8I5KVQ4, A0ACI8UIC3

  20. XM_054377945.1 → XP_054233920.1  myocyte-specific enhancer factor 2A isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z454, A0ACI8UIC7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02078.1 GenPept UniProtKB/Swiss-Prot:Q02078

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