U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRDX4 peroxiredoxin 4 [ Gallus gallus (chicken) ]

Gene ID: 418601, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
PRDX4provided by CGNC
Official Full Name
peroxiredoxin 4provided by CGNC
Primary source
CGNC:12239
See related
Ensembl:ENSGALG00010003214
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (118460697..118469165, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (118489442..118497908, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene spermidine/spermine N1-acetyltransferase 1 Neighboring gene acyl-CoA thioesterase 9 Neighboring gene uncharacterized LOC112531487 Neighboring gene uncharacterized LOC121109098 Neighboring gene uncharacterized LOC112531488

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Yan Y, et al. Nat Commun, 2015 May 6. PMID 25943695, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thioredoxin peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
peroxiredoxin-4
XP_001234000.1
XP_040514027.1
XP_040514028.1
XP_046765902.1
XP_046768309.1
XP_416800.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    118460697..118469165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416800.8 → XP_416800.2  peroxiredoxin-4 isoform X2

    Related
    ENSGALP00010004490.1, ENSGALT00010007517.1
    Conserved Domains (1) summary
    cd03015
    Location:75 → 246
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

  2. XM_001233999.5 → XP_001234000.1  peroxiredoxin-4 isoform X3

    UniProtKB/TrEMBL
    A0A1D5PLH7
    Related
    ENSGALP00010004487.1, ENSGALT00010007511.1
    Conserved Domains (1) summary
    cd03015
    Location:75 → 246
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

  3. XM_046912353.1 → XP_046768309.1  peroxiredoxin-4 isoform X1

    Related
    ENSGALP00010004489.1, ENSGALT00010007515.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    118489442..118497908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040658094.2 → XP_040514028.1  peroxiredoxin-4 isoform X2

    Conserved Domains (1) summary
    cd03015
    Location:75 → 246
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

  2. XM_040658093.2 → XP_040514027.1  peroxiredoxin-4 isoform X3

    UniProtKB/TrEMBL
    A0A1D5PLH7
    Conserved Domains (1) summary
    cd03015
    Location:75 → 246
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

  3. XM_046909946.1 → XP_046765902.1  peroxiredoxin-4 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.