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CYP2D15 cytochrome P450 2D [ Canis lupus familiaris (dog) ]

Gene ID: 415120, updated on 18-Sep-2024

Summary

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Gene symbol
CYP2D15
Gene description
cytochrome P450 2D
See related
Ensembl:ENSCAFG00845014943
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CYP2D; CYPIID15
Orthologs
human all
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Genomic context

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See CYP2D15 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (24000262..24004211)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (23190268..23194223)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (24212712..24216661)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (23717484..23721432)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (24037966..24041898)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene transcription factor 20 Neighboring gene uncharacterized LOC102151248 Neighboring gene microRNA mir-8829 Neighboring gene uncharacterized LOC111097639 Neighboring gene NADH:ubiquinone oxidoreductase subunit A6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and characterization of canine cytochrome P450 2D15. Roussel F, et al. Arch Biochem Biophys, 1998 Sep 1. PMID 9721180
  2. Expression and characterization of dog CYP2D15 using baculovirus expression system. Tasaki T, et al. J Biochem, 1998 Jan. PMID 9504424
  3. A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization. Sakamoto K, et al. Arch Biochem Biophys, 1995 Jun 1. PMID 7786018
  4. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature, 2005 Dec 8. PMID 16341006

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in arachidonate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in xenobiotic metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytochrome P450 2D15
Names
Cytochrome-P450-2D15
cytochrome P450 DUT2
cytochrome P450, family 2, subfamily D, polypeptide 15
monooxygenase
NP_001003333.1
XP_038534693.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003333.1 → NP_001003333.1  cytochrome P450 2D15

    See identical proteins and their annotated locations for NP_001003333.1

    Status: PROVISIONAL

    Source sequence(s)
    D17397
    UniProtKB/Swiss-Prot
    O02859, Q29473
    UniProtKB/TrEMBL
    X5KNW5
    Related
    ENSCAFP00845021089.1, ENSCAFT00845026775.1
    Conserved Domains (1) summary
    pfam00067
    Location:37 → 497
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    24000262..24004211
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038678765.1 → XP_038534693.1  cytochrome P450 2D15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SP41, X5KCU7, X5KNV4
    Related
    ENSCAFP00845021103.1, ENSCAFT00845026798.1
    Conserved Domains (1) summary
    cl41757
    Location:68 → 444
    cytochrome_P450; cytochrome P450 (CYP) superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    23717484..23721432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    24037966..24041898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    24212712..24216661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23190268..23194223
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29473.3 GenPept UniProtKB/Swiss-Prot:Q29473

Gene LinkOut

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Molecular Biology Databases
Research Materials