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LCN10 lipocalin 10 [ Homo sapiens (human) ]

Gene ID: 414332, updated on 5-Mar-2024

Summary

Official Symbol
LCN10provided by HGNC
Official Full Name
lipocalin 10provided by HGNC
Primary source
HGNC:HGNC:20892
See related
Ensembl:ENSG00000187922 MIM:612904; AllianceGenome:HGNC:20892
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Members of the lipocalin family, such as LCN10, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Expression
Broad expression in spleen (RPKM 4.2), endometrium (RPKM 3.9) and 19 other tissues See more
Orthologs
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Genomic context

See LCN10 in Genome Data Viewer
Location:
9q34.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136738170..136742940, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148971348..148976118, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139632622..139637392, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene cuticle collagen 2-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20538 Neighboring gene small nucleolar RNA, H/ACA box 17B Neighboring gene small nucleolar RNA host gene 7 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:139623217-139623386 Neighboring gene small nucleolar RNA, H/ACA box 17A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29323 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139627044-139627888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139629713-139630212 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20539 Neighboring gene uncharacterized LOC100128593 Neighboring gene lipocalin 6 Neighboring gene microRNA 6722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29324 Neighboring gene lipocalin 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General protein information

Preferred Names
epididymal-specific lipocalin-10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001712.3NP_001001712.2  epididymal-specific lipocalin-10 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001001712.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AL355987
    Consensus CDS
    CCDS35182.2
    UniProtKB/TrEMBL
    B7ZMD1
    Related
    ENSP00000418491.1, ENST00000497771.6
  2. NM_001368089.1NP_001355018.1  epididymal-specific lipocalin-10 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL355987, AY301271
    Consensus CDS
    CCDS94536.1
    UniProtKB/Swiss-Prot
    A2RUU3, B0QZ79, Q6JVE6
    Related
    ENSP00000420564.1, ENST00000474369.1
  3. NM_001368090.1NP_001355019.1  epididymal-specific lipocalin-10 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL355987, BC144441
    Consensus CDS
    CCDS94537.1
    UniProtKB/TrEMBL
    B7ZMD1, E9PK15
    Related
    ENSP00000431726.1, ENST00000527229.5
    Conserved Domains (1) summary
    cl10502
    Location:36108
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

RNA

  1. NR_160514.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL355987, BC171741
  2. NR_160515.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL355987, HY166769
  3. NR_160516.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL355987, DA965366
  4. NR_160517.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL355987
    Related
    ENST00000341040.11

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    136738170..136742940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    148971348..148976118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)