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LCN6 lipocalin 6 [ Homo sapiens (human) ]

Gene ID: 158062, updated on 27-Nov-2024

Summary

Official Symbol
LCN6provided by HGNC
Official Full Name
lipocalin 6provided by HGNC
Primary source
HGNC:HGNC:17337
See related
Ensembl:ENSG00000267206 MIM:609379; AllianceGenome:HGNC:17337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LCN5; hLcn5; UNQ643
Summary
Predicted to enable small molecule binding activity. Predicted to be involved in single fertilization. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in endometrium (RPKM 3.6), heart (RPKM 2.2) and 16 other tissues See more
Orthologs
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Genomic context

See LCN6 in Genome Data Viewer
Location:
9q34.3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136744017..136748525, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148977195..148981703, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139638469..139642977, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene cuticle collagen 2-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20538 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:139623217-139623386 Neighboring gene small nucleolar RNA host gene 7 Neighboring gene small nucleolar RNA, H/ACA box 17A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29323 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139627044-139627888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139629713-139630212 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20539 Neighboring gene lipocalin 10 Neighboring gene uncharacterized LOC100128593 Neighboring gene microRNA 6722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29324 Neighboring gene lipocalin 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139657693-139658340 Neighboring gene lipocalin 15

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Potential readthrough

Included gene: LCN10

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in single fertilization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
epididymal-specific lipocalin-6
Names
epididymal-specific lipocalin LCN6
epididymis secretory sperm binding protein
lipocalin 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198946.3NP_945184.1  epididymal-specific lipocalin-6 precursor

    See identical proteins and their annotated locations for NP_945184.1

    Status: VALIDATED

    Source sequence(s)
    AF303084, BC062746
    Consensus CDS
    CCDS7005.1
    UniProtKB/Swiss-Prot
    B0QZ80, P62502, Q71SF6
    UniProtKB/TrEMBL
    A0A024R8I9, H7C1C5
    Related
    ENSP00000339621.3, ENST00000341206.9
    Conserved Domains (1) summary
    pfam00061
    Location:32160
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    136744017..136748525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    148977195..148981703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)