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SLC25A53 solute carrier family 25 member 53 [ Homo sapiens (human) ]

Gene ID: 401612, updated on 21-Dec-2019

Summary

Official Symbol
SLC25A53provided by HGNC
Official Full Name
solute carrier family 25 member 53provided by HGNC
Primary source
HGNC:HGNC:31894
See related
Ensembl:ENSG00000269743 MIM:300941
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MCART6
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See SLC25A53 in Genome Data Viewer
Location:
Xq22.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (104099214..104157009, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (103343898..103401708, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 3 pseudogene Neighboring gene H2B.W histone 3, pseudogene Neighboring gene zinc finger CCHC-type containing 18 Neighboring gene uncharacterized LOC286437 Neighboring gene family with sequence similarity 199, X-linked Neighboring gene ESX homeobox 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686O1267

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 25 member 53
Names
mitochondrial carrier triple repeat protein 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012755.5NP_001012773.2  solute carrier family 25 member 53

    See identical proteins and their annotated locations for NP_001012773.2

    Status: VALIDATED

    Source sequence(s)
    AC234783, AL833609, BC140814
    Consensus CDS
    CCDS35363.1
    UniProtKB/Swiss-Prot
    Q5H9E4
    Related
    ENSP00000468980.1, ENST00000594199.3
    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    104099214..104157009 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005262129.5XP_005262186.1  solute carrier family 25 member 53 isoform X2

    See identical proteins and their annotated locations for XP_005262186.1

    UniProtKB/Swiss-Prot
    Q5H9E4
    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein
  2. XM_011530953.3XP_011529255.1  solute carrier family 25 member 53 isoform X2

    See identical proteins and their annotated locations for XP_011529255.1

    UniProtKB/Swiss-Prot
    Q5H9E4
    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein
  3. XM_024452380.1XP_024308148.1  solute carrier family 25 member 53 isoform X2

    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein
  4. XM_011530952.3XP_011529254.1  solute carrier family 25 member 53 isoform X2

    See identical proteins and their annotated locations for XP_011529254.1

    UniProtKB/Swiss-Prot
    Q5H9E4
    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein
  5. XM_017029515.2XP_016885004.1  solute carrier family 25 member 53 isoform X1

  6. XM_017029514.2XP_016885003.1  solute carrier family 25 member 53 isoform X1

  7. XM_017029516.2XP_016885005.1  solute carrier family 25 member 53 isoform X2

    UniProtKB/Swiss-Prot
    Q5H9E4
    Conserved Domains (1) summary
    cl28162
    Location:110203
    Mito_carr; Mitochondrial carrier protein
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