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HERC2P2 HERC2 pseudogene 2 [ Homo sapiens (human) ]

Gene ID: 400322, updated on 22-Oct-2024

Summary

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Official Symbol
HERC2P2provided by HGNC
Official Full Name
HERC2 pseudogene 2provided by HGNC
Primary source
HGNC:HGNC:4870
See related
Ensembl:ENSG00000291003 AllianceGenome:HGNC:4870
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MN7; D15F37S3
Expression
Ubiquitous expression in urinary bladder (RPKM 32.1), brain (RPKM 25.7) and 25 other tissues See more
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Genomic context

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See HERC2P2 in Genome Data Viewer
Location:
15q11.2
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (22494837..22590831)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (20166952..20262941)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (23282265..23378259, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene pectinesterase inhibitor 10-like Neighboring gene HERC2 pseudogene 7 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:23375324-23375978 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:23311731-23312230 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:23306154-23306733 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 2 pseudogene Neighboring gene uncharacterized LOC101927846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:23263501-23264001 Neighboring gene RNA, 7SL, cytoplasmic 495, pseudogene Neighboring gene golgin A8 family member I, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of long non-coding RNA HERC2P2 as a tumor suppressor in glioma. Yang C, et al. Carcinogenesis, 2019 Aug 22. PMID 30809632
  2. A putative gene family in 15q11-13 and 16p11.2: possible implications for Prader-Willi and Angelman syndromes. Buiting K, et al. Proc Natl Acad Sci U S A, 1992 Jun 15. PMID 1608955, Free PMC Article
  3. Expressed copies of the MN7 (D15F37) gene family map close to the common deletion breakpoints in the Prader-Willi/Angelman syndromes. Buiting K, et al. Cytogenet Cell Genet, 1998. PMID 9730612
  4. The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities. Ji Y, et al. Hum Mol Genet, 1999 Mar. PMID 9949213
  5. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Nagase T, et al. DNA Res, 1997 Apr 28. PMID 9205841

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • hect domain and RLD 2 pseudogene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002824.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA976147, AB002391, AC100757, AF041080, DB069140
    Related
    ENST00000619021.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    22494837..22590831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_021160017.1 Reference GRCh38.p14 PATCHES

    Range
    3388384..3485185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187604.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    138448..235204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    20166952..20262941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001024681.1: Suppressed sequence

    Description
    NM_001024681.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version

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