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ANGPT2 angiopoietin 2 [ Gallus gallus (chicken) ]

Gene ID: 395610, updated on 17-Aug-2024

Summary

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Symbol
ANGPT2provided by CGNC
Full Name
angiopoietin 2provided by CGNC
Primary source
CGNC:49399
See related
Ensembl:ENSGALG00010002288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ANGIOPOIETIN-2
Orthologs
human mouse all
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Genomic context

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See ANGPT2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (88275880..88322057)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (88080739..88126913)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 14A Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 Neighboring gene uncharacterized LOC124418358 Neighboring gene microcephalin 1 Neighboring gene uncharacterized LOC121110164 Neighboring gene uncharacterized LOC107053150 Neighboring gene uncharacterized LOC121110165

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a novel form of angiopoietin-2 (Ang-2B) and expression of VEGF and angiopoietin-2 during chicken testicular development and regression. Mezquita J, et al. Biochem Biophys Res Commun, 1999 Jul 5. PMID 10403795
  2. Expression of angiopoietin 1 and 2 in ectopic endometrium on the chicken chorioallantoic membrane. Drenkhahn M, et al. Fertil Steril, 2004 Mar. PMID 15019822
  3. Genomic structure and alternative splicing of chicken angiopoietin-2. Mezquita J, et al. Biochem Biophys Res Commun, 2000 Aug 28. PMID 10964717

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Tie signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiopoietin-2
Names
Angiopoietin-2B (Ang-2B)
angiopoietin-2A
angiopoietin-2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396167.1 → NP_001383096.1  angiopoietin-2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000065
    UniProtKB/TrEMBL
    Q9DER0
    Related
    ENSGALP00010003065.1, ENSGALT00010005198.1
    Conserved Domains (2) summary
    smart00186
    Location:225 → 439
    FBG; Fibrinogen-related domains (FReDs)
    COG1196
    Location:75 → 224
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. NM_001396168.1 → NP_001383097.1  angiopoietin-2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000065
    UniProtKB/TrEMBL
    Q9DER2, Q9PU54
    Related
    ENSGALP00010003062.1, ENSGALT00010005195.1
    Conserved Domains (2) summary
    TIGR01612
    Location:78 → 261
    235kDa-fam; reticulocyte binding/rhoptry protein
    smart00186
    Location:277 → 491
    FBG; Fibrinogen-related domains (FReDs)

  3. NM_204817.2 → NP_990148.2  angiopoietin-2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000065
    UniProtKB/TrEMBL
    Q9DER1, Q9PU54
    Related
    ENSGALP00010003059.1, ENSGALT00010005192.1
    Conserved Domains (2) summary
    smart00186
    Location:191 → 405
    FBG; Fibrinogen-related domains (FReDs)
    COG1196
    Location:2 → 190
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    88275880..88322057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938432.1 → XP_046794388.1  angiopoietin-2 isoform X1

    UniProtKB/TrEMBL
    Q9PU54

  2. XM_046938433.1 → XP_046794389.1  angiopoietin-2 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    88080739..88126913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913014.1 → XP_046768970.1  angiopoietin-2 isoform X1

    UniProtKB/TrEMBL
    Q9PU54

  2. XM_046913015.1 → XP_046768971.1  angiopoietin-2 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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