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CG32369 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38873, updated on 18-Sep-2024

Summary

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Official Symbol
CG32369provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052369
Locus tag
Dmel_CG32369
See related
AllianceGenome:FB:FBgn0052369
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13684; CG7388; Dmel\CG32369
Summary
Predicted to enable zinc ion binding activity. Is expressed in embryonic/larval midgut; embryonic/larval midgut primordium; embryonic/larval visceral muscle cell; and longitudinal visceral muscle primordium. Orthologous to several human genes including LONRF2 (LON peptidase N-terminal domain and ring finger 2) and LONRF3 (LON peptidase N-terminal domain and ring finger 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
66A13-66A14; 3-21 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7777105..7809825, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7770205..7802925, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Henna Neighboring gene Clock Neighboring gene PAR-domain protein 1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme. Terriente-Felix A, et al. Development, 2013 Feb. PMID 23325760, Free PMC Article
  2. Genome-wide identification of hypoxia-induced enhancer regions. Kamps-Hughes N, et al. PeerJ, 2015. PMID 26713262, Free PMC Article
  3. Transcriptome analysis of Drosophila melanogaster laboratory strains of different geographical origin after long-term laboratory maintenance. Zarubin M, et al. Ecol Evol, 2020 Jul. PMID 32760513, Free PMC Article
  4. RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides. Abruzzi KC, et al. PLoS Genet, 2017 Feb. PMID 28182648, Free PMC Article
  5. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c7800761-7793767 mobile_element_type = transposon:297{}950

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG32369-PA
CG32369-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7777105..7809825 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259731.3 → NP_001246660.1  uncharacterized protein Dmel_CG32369, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246660.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG83, Q9VSB2
    Conserved Domains (6) summary
    cd00162
    Location:687 → 729
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cl19481
    Location:791 → 1005
    LON; Found in ATP-dependent protease La (LON)
    sd00006
    Location:350 → 378
    TPR; TPR repeat [structural motif]
    pfam02190
    Location:802 → 1001
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
    pfam13414
    Location:349 → 412
    TPR_11; TPR repeat
    cl17238
    Location:183 → 206
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

  2. NM_168232.3 → NP_729296.1  uncharacterized protein Dmel_CG32369, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729296.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG83, Q9VSB2
    Related
    FBpp0076498
    Conserved Domains (6) summary
    cd00162
    Location:687 → 729
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cl19481
    Location:791 → 1005
    LON; Found in ATP-dependent protease La (LON)
    sd00006
    Location:350 → 378
    TPR; TPR repeat [structural motif]
    pfam02190
    Location:802 → 1001
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
    pfam13414
    Location:349 → 412
    TPR_11; TPR repeat
    cl17238
    Location:183 → 206
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IG83 Q8IG83
Q9VSB1 Q9VSB1
Q9VSB2 Q9VSB2

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