Format

Send to:

Choose Destination

C1QTNF12 C1q and TNF related 12 [ Homo sapiens (human) ]

Gene ID: 388581, updated on 17-Nov-2020

Summary

Official Symbol
C1QTNF12provided by HGNC
Official Full Name
C1q and TNF related 12provided by HGNC
Primary source
HGNC:HGNC:32308
See related
Ensembl:ENSG00000184163 MIM:616593
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1QDC2; CTRP12; FAM132A
Expression
Biased expression in duodenum (RPKM 4.0), small intestine (RPKM 3.7) and 7 other tissues See more
Orthologs

Genomic context

See C1QTNF12 in Genome Data Viewer
Location:
1p36.33
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (1242448..1247218, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1177826..1182102, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene stromal cell derived factor 4 Neighboring gene beta-1,3-galactosyltransferase 6 Neighboring gene ubiquitin conjugating enzyme E2 J2 Neighboring gene long intergenic non-protein coding RNA 1786

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Clone Names

  • MGC105127

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hormone activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hormone activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
negative regulation of gluconeogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 
positive regulation of glucose import IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of insulin receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein kinase B signaling IEA
Inferred from Electronic Annotation
more info
 
regulation of glucose import ISS
Inferred from Sequence or Structural Similarity
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
adipolin
Names
C1q and TNF related protein 12
C1q and tumor necrosis factor related protein 12
C1q domain containing 2
C1q/TNF-related protein 12
adipose-derived insulin-sensitizing factor
complement C1q tumor necrosis factor-related protein 12
family with sequence similarity 132 member A
protein FAM132A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014980.3NP_001014980.1  adipolin precursor

    See identical proteins and their annotated locations for NP_001014980.1

    Status: VALIDATED

    Source sequence(s)
    BC089443
    Consensus CDS
    CCDS30554.1
    UniProtKB/Swiss-Prot
    Q5T7M4
    Related
    ENSP00000329137.2, ENST00000330388.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    1242448..1247218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541437.1XP_011539739.1  adipolin isoform X4

  2. XM_011541436.2XP_011539738.1  adipolin isoform X3

  3. XM_011541435.2XP_011539737.1  adipolin isoform X2

  4. XM_024446907.1XP_024302675.1  adipolin isoform X1

Support Center