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C16orf86 chromosome 16 open reading frame 86 [ Homo sapiens (human) ]

Gene ID: 388284, updated on 5-Aug-2022

Summary

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Official Symbol
C16orf86provided by HGNC
Official Full Name
chromosome 16 open reading frame 86provided by HGNC
Primary source
HGNC:HGNC:33755
See related
Ensembl:ENSG00000159761 AllianceGenome:HGNC:33755
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 6.3), fat (RPKM 1.3) and 19 other tissues See more
Orthologs
mouse all
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Genomic context

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See C16orf86 in Genome Data Viewer
Location:
16q22.1
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (67666814..67668755)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (73461582..73463523)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (67700717..67702658)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene par-6 family cell polarity regulator alpha Neighboring gene enkurin domain containing 1 Neighboring gene glucose-fructose oxidoreductase domain containing 2 Neighboring gene RAN binding protein 10 Neighboring gene Sharpr-MPRA regulatory region 12647

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Biological insights from 108 schizophrenia-associated genetic loci. Schizophrenia Working Group of the Psychiatric Genomics Consortium.. Nature, 2014 Jul 24. PMID 25056061, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein C16orf86

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012984.3 → NP_001013002.2  uncharacterized protein C16orf86

    See identical proteins and their annotated locations for NP_001013002.2

    Status: VALIDATED

    Source sequence(s)
    AC010530, BC032064, CA432406
    Consensus CDS
    CCDS32468.2
    UniProtKB/Swiss-Prot
    B5MCW6, Q6ZW13
    Related
    ENSP00000384117.3, ENST00000403458.9
    Conserved Domains (1) summary
    pfam15762
    Location:1 → 184
    DUF4691; Domain of unknown function (DUF4691)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    67666814..67668755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434097.1 → XP_047290053.1  uncharacterized protein C16orf86 isoform X1

  2. XM_047434098.1 → XP_047290054.1  uncharacterized protein C16orf86 isoform X2

  3. XM_005255952.6 → XP_005256009.1  uncharacterized protein C16orf86 isoform X3

    Conserved Domains (1) summary
    pfam15762
    Location:1 → 184
    DUF4691; Domain of unknown function (DUF4691)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    73461582..73463523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZW13.2 GenPept UniProtKB/Swiss-Prot:Q6ZW13

Gene LinkOut

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