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Slc6a16 solute carrier family 6, member 16 [ Mus musculus (house mouse) ]

Gene ID: 381884, updated on 2-Nov-2024

Summary

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Official Symbol
Slc6a16provided by MGI
Official Full Name
solute carrier family 6, member 16provided by MGI
Primary source
MGI:MGI:2685930
See related
Ensembl:ENSMUSG00000094152 AllianceGenome:MGI:2685930
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1084
Summary
Predicted to be involved in amino acid transport and sodium ion transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human SLC6A16 (solute carrier family 6 member 16). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 27.4) See more
Orthologs
human all
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Genomic context

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See Slc6a16 in Genome Data Viewer
Location:
7 B3; 7 29.22 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44890177..44922789)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45240753..45273365)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene TEA domain family member 2 Neighboring gene STARR-seq mESC enhancer starr_18834 Neighboring gene STARR-positive B cell enhancer ABC_E872 Neighboring gene STARR-seq mESC enhancer starr_18835 Neighboring gene CD37 antigen Neighboring gene predicted gene, 23585 Neighboring gene solute carrier family 6 member 21 Neighboring gene STARR-positive B cell enhancer ABC_E6543 Neighboring gene predicted gene, 39006

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001324535.1 → NP_001311464.1  orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

    Status: PROVISIONAL

    Source sequence(s)
    AC150897
    Consensus CDS
    CCDS90233.1
    UniProtKB/TrEMBL
    A0A1L1SR47, A0A1L1SVE2
    Related
    ENSMUSP00000149306.2, ENSMUST00000213347.2
    Conserved Domains (1) summary
    cl00456
    Location:125 → 694
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    44890177..44922789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153198.1 → XP_036009091.1  orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 isoform X1

    UniProtKB/TrEMBL
    A0A1L1SVE2
    Conserved Domains (1) summary
    cl00456
    Location:125 → 612
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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