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CG3894 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37959, updated on 18-Sep-2024

Summary

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Official Symbol
CG3894provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035059
Locus tag
Dmel_CG3894
See related
AllianceGenome:FB:FBgn0035059
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9197; Dmel\CG3894
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in intracellular signal transduction. Orthologous to human NEURL2 (neuralized E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
60E1-60E1; 2-107 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24763167..24766750)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20650690..20654273)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene spatzle 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glutathione S transferase E12 Neighboring gene Epidermal growth factor receptor pathway substrate clone 15 Neighboring gene antisense RNA:CR44067 Neighboring gene eggless

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Euchromatic transposon insertions trigger production of novel Pi- and endo-siRNAs at the target sites in the drosophila germline. Shpiz S, et al. PLoS Genet, 2014 Feb. PMID 24516406, Free PMC Article
  2. Identification of expressed transposable element insertions in the sequenced genome of Drosophila melanogaster. Deloger M, et al. Gene, 2009 Jun 15. PMID 19332112
  3. Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster. Schrider DR, et al. Genome Res, 2011 Dec. PMID 22135405, Free PMC Article
  4. A genome-wide RNAi screen reveals multiple regulators of caspase activation. Yi CH, et al. J Cell Biol, 2007 Nov 19. PMID 17998402, Free PMC Article
  5. Stonewalling Drosophila stem cell differentiation by epigenetic controls. Maines JZ, et al. Development, 2007 Apr. PMID 17344229

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: 24763666-24765583 mobile_element_type = transposon:G2{}CG3894[iso-1]

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3894-PC
dmNeural-like

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24763167..24766750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138119.7 → NP_611963.5  uncharacterized protein Dmel_CG3894 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611963.5

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W112
    Conserved Domains (2) summary
    cd03717
    Location:283 → 321
    SOCS_SOCS_like; SOCS (suppressors of cytokine signaling) box of SOCS-like proteins. The CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. These intracellular proteins regulate the responses of immune cells to ...
    cd12887
    Location:64 → 280
    SPRY_NHR_like; SPRY domain in neuralized homology repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MRU1 Q8MRU1
Q9W112 Q9W112

Gene LinkOut

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