U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sesn1.L sestrin 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379559, updated on 18-Sep-2024

Summary

Official Symbol
sesn1.L
Official Full Name
sestrin 1 L homeolog
Primary source
Xenbase:XB-GENE-866080
Locus tag
XELAEV_18027202mg
See related
EnsemblRapid:ENSXLAG00005034486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
PA26; sesn1; sesn1-A
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 5L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (81458295..81595071)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (79376843..79389637)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 162 L homeolog Neighboring gene centrosomal protein 57kDa-like 1 L homeolog Neighboring gene armadillo repeat containing 2 L homeolog Neighboring gene forkhead box O3 L homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC69031

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 
enables L-leucine binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of GATOR2 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
sestrin-1
Names
XPA26
nuclear factor XPA26-T2
p53-regulated protein PA26
sestrin 1,nuclear factor XPA26-T2
NP_001079869.1
XP_041418007.1
XP_041418008.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086400.1NP_001079869.1  sestrin-1

    See identical proteins and their annotated locations for NP_001079869.1

    Status: PROVISIONAL

    Source sequence(s)
    AB048259
    UniProtKB/Swiss-Prot
    P58003, Q5D077
    UniProtKB/TrEMBL
    A0A974CVT4
    Related
    ENSXLAP00005103137.1, ENSXLAT00005105141.1
    Conserved Domains (1) summary
    pfam04636
    Location:39480
    PA26; PA26 p53-induced protein (sestrin)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    81458295..81595071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562073.1XP_041418007.1  sestrin-1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1KL11
  2. XM_041562074.1XP_041418008.1  sestrin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1KMQ6