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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_002226.5 → NP_002217.3 protein jagged-2 isoform a precursor
See identical proteins and their annotated locations for NP_002217.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
- Source sequence(s)
-
AA775404, AF003521, AF029778, AI276672, AJ712299, AL512356, BX105691, U69180
- Consensus CDS
-
CCDS9998.1
- UniProtKB/Swiss-Prot
- Q9Y219, Q9Y6Q0
- Related
- ENSP00000328169.3, ENST00000331782.8
- Conserved Domains (5) summary
-
- smart00215
Location:872 → 943
- VWC_out; von Willebrand factor (vWF) type C domain
- cd00054
Location:307 → 345
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- pfam00008
Location:351 → 381
- EGF; EGF-like domain
- pfam01414
Location:178 → 240
- DSL; Delta serrate ligand
- pfam07657
Location:28 → 102
- MNNL; N terminus of Notch ligand
-
NM_145159.3 → NP_660142.1 protein jagged-2 isoform b precursor
See identical proteins and their annotated locations for NP_660142.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in a shorter protein (isoform b) than isoform a encoded by variant 1. Isoform b is also known as hJAG2.del-E6.
- Source sequence(s)
-
AA775404, AF003521, AF029779, AI276672, AJ712299, AL512356, BX105691, U69180
- Consensus CDS
-
CCDS9999.1
- UniProtKB/Swiss-Prot
-
Q9Y219
- Related
- ENSP00000328566.2, ENST00000347004.2
- Conserved Domains (5) summary
-
- smart00215
Location:834 → 905
- VWC_out; von Willebrand factor (vWF) type C domain
- cd00054
Location:307 → 345
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- pfam00008
Location:351 → 381
- EGF; EGF-like domain
- pfam01414
Location:178 → 240
- DSL; Delta serrate ligand
- pfam07657
Location:28 → 102
- MNNL; N terminus of Notch ligand
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
105140995..105168776 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047431352.1 → XP_047287308.1 protein jagged-2 isoform X1
-
XM_047431353.1 → XP_047287309.1 protein jagged-2 isoform X2
-
XM_047431354.1 → XP_047287310.1 protein jagged-2 isoform X3
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
99382854..99410701 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)