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CASTOR3 CASTOR family member 3 [ Homo sapiens (human) ]

Gene ID: 352954, updated on 1-Jun-2020

Summary

Official Symbol
CASTOR3provided by HGNC
Official Full Name
CASTOR family member 3provided by HGNC
Primary source
HGNC:HGNC:29954
See related
Ensembl:ENSG00000239521
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GATS; STAG3OS
Expression
Broad expression in brain (RPKM 17.6), testis (RPKM 9.6) and 22 other tissues See more
Orthologs

Genomic context

See CASTOR3 in Genome Data Viewer
Location:
7q22.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (100200653..100272232, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (99798276..99869855, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L29-like Neighboring gene glypican 2 Neighboring gene stromal antigen 3 Neighboring gene uncharacterized LOC107986828 Neighboring gene uncharacterized LOC105375427 Neighboring gene PVR related immunoglobulin domain containing Neighboring gene uncharacterized LOC105375426 Neighboring gene STAG3L5P-PVRIG2P-PILRB readthrough Neighboring gene speedy/RINGO cell cycle regulator family member E3 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 1 Neighboring gene stromal antigen 3-like 5 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • GATS, stromal antigen 3 opposite strand
  • STAG3 opposite strand transcript protein
  • opposite strand transcription unit to STAG3
  • putative protein CASTOR 3
  • putative protein GATS
  • stromal antigen 3 opposite strand

Clone Names

  • DKFZp686B07267

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cellular response to L-arginine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with GATOR2 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028038.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice pattern in the 3' UTR, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK092358, AL831967, DA737015
  2. NR_028039.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice pattern in the 3' UTR, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK092358, BC090867, DA737015, H18847
    Related
    ENST00000328453.9
  3. NR_028040.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice pattern in the 3' UTR, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK092358, AK290510, BC090867, DA737015, H18847
    Related
    ENST00000543273.5
  4. NR_166147.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC005071, AC073842

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    100200653..100272232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178831.6: Suppressed sequence

    Description
    NM_178831.6: This RefSeq was removed because it is now thought that this gene is a pseudogene.
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