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ANKDD1A ankyrin repeat and death domain containing 1A [ Homo sapiens (human) ]

Gene ID: 348094, updated on 25-Jan-2022

Summary

Official Symbol
ANKDD1Aprovided by HGNC
Official Full Name
ankyrin repeat and death domain containing 1Aprovided by HGNC
Primary source
HGNC:HGNC:28002
See related
Ensembl:ENSG00000166839 AllianceGenome:HGNC:28002
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in signal transduction. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in adrenal (RPKM 13.1), spleen (RPKM 12.2) and 24 other tissues See more
Orthologs
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Genomic context

See ANKDD1A in Genome Data Viewer
Location:
15q22.31
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (64911902..64958691)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (65204101..65251033)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene PIF1 5'-to-3' DNA helicase Neighboring gene pleckstrin homology domain containing O2 Neighboring gene uncharacterized LOC107984754 Neighboring gene SPG21 abhydrolase domain containing, maspardin Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene transmembrane protein 126A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ18078, FLJ25870, MGC120305, MGC120306, MGC120307

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ankyrin repeat and death domain-containing protein 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_182703.6NP_874362.3  ankyrin repeat and death domain-containing protein 1A

    See identical proteins and their annotated locations for NP_874362.3

    Status: VALIDATED

    Source sequence(s)
    AC103691, AK098736, AK307698, BC042002, BC047571, BC101273, BC101275, BX116779
    Consensus CDS
    CCDS10197.2
    UniProtKB/Swiss-Prot
    Q495B1
    Related
    ENSP00000325895.9, ENST00000319580.13
    Conserved Domains (4) summary
    cd00204
    Location:186311
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01670
    Location:426494
    Death; Death Domain: a protein-protein interaction domain
    pfam12796
    Location:163253
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:260288
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    64911902..64958691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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