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LANCL3 LanC like 3 [ Homo sapiens (human) ]

Gene ID: 347404, updated on 11-Jun-2021

Summary

Official Symbol
LANCL3provided by HGNC
Official Full Name
LanC like 3provided by HGNC
Primary source
HGNC:HGNC:24767
See related
Ensembl:ENSG00000147036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See LANCL3 in Genome Data Viewer
Location:
Xp21.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (37571661..37684463)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (37430914..37543716)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ferritin heavy chain 1 pseudogene 27 Neighboring gene family with sequence similarity 47 member D, pseudogene Neighboring gene H2A.L variant histone 1M, pseudogene Neighboring gene X-linked Kx blood group Neighboring gene cytochrome b-245 beta chain

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ42925

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
lanC-like protein 3
Names
LanC lantibiotic synthetase component C-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016368.1 RefSeqGene

    Range
    5001..110929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170331.2NP_001163802.1  lanC-like protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001163802.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift compared to variant 1. The encoded isoform (2) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC233297, AI989993, AK124915, BG944288
    Consensus CDS
    CCDS55398.1
    UniProtKB/Swiss-Prot
    Q6ZV70
    Related
    ENSP00000367882.4, ENST00000378619.4
    Conserved Domains (1) summary
    cd04794
    Location:65414
    euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein
  2. NM_198511.3NP_940913.1  lanC-like protein 3 isoform 1

    See identical proteins and their annotated locations for NP_940913.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AC233297, AI989993, AK124915, BG944288
    Consensus CDS
    CCDS14240.1
    UniProtKB/Swiss-Prot
    Q6ZV70
    Related
    ENSP00000367885.3, ENST00000378621.7
    Conserved Domains (1) summary
    cd04794
    Location:65367
    euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    37571661..37684463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543904.2XP_011542206.1  lanC-like protein 3 isoform X1

    Conserved Domains (1) summary
    cd04794
    Location:7232
    euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein
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