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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029141.2 RefSeqGene
- Range
-
14938..60182
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001206567.2 → NP_001193496.1 gamma-interferon-inducible protein 16 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks an in-frame exon in the 5' coding region and has an additional in-frame exon in the 3' coding region, compared to variant 2. The additional exon is described as exon 7a in PMID:9718316. The resulting isoform (1) is of the same size but lacks a segment in the N-terminal region and has an additional segment in the C-terminal region, compared to isoform 2. Note the CDS was annotated to initiate translation from an in-frame downstream AUG, as it is flanked by a strong Kozak signal, and is better conserved than the upstream AUG located 4 codons upstream.
- Source sequence(s)
-
AK296228, BM806453, DA945454, DB273519, M63838
- Consensus CDS
-
CCDS58039.1
- UniProtKB/Swiss-Prot
-
Q16666
- Related
- ENSP00000352740.3, ENST00000359709.7
- Conserved Domains (3) summary
-
- cd08305
Location:10 → 83
- Pyrin; Pyrin: a protein-protein interaction domain
- pfam02760
Location:145 → 313
- HIN; HIN-200/IF120x domain
- pfam06583
Location:343 → 545
- Neogenin_C; Neogenin C-terminus
-
NM_001364867.2 → NP_001351796.1 gamma-interferon-inducible protein 16 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) encodes the longest isoform (3, also known as IFI 16A).
- Source sequence(s)
-
AL359753
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_001376587.1 → NP_001363516.1 gamma-interferon-inducible protein 16 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL359753
- Related
- ENSP00000295809.7, ENST00000295809.12
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_001376588.1 → NP_001363517.1 gamma-interferon-inducible protein 16 isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359753
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_001376589.1 → NP_001363518.1 gamma-interferon-inducible protein 16 isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL359753
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_001376591.1 → NP_001363520.1 gamma-interferon-inducible protein 16 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AL359753
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_001376592.1 → NP_001363521.1 gamma-interferon-inducible protein 16 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AL359753
- Related
- ENSP00000404325.2, ENST00000448393.6
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
-
NM_005531.3 → NP_005522.2 gamma-interferon-inducible protein 16 isoform 2
See identical proteins and their annotated locations for NP_005522.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) consists of 11 exons and encodes isoform 2 (also known as isoform B, PMIDs:9718316 and 12588705). Note the CDS was annotated to initiate translation from an in-frame downstream AUG, as it is flanked by a strong Kozak signal, and is better conserved than the upstream AUG located 4 codons upstream.
- Source sequence(s)
-
AL359753, BC017059, DA990524, M63838
- Consensus CDS
-
CCDS1180.3
- UniProtKB/Swiss-Prot
-
Q16666
- Related
- ENSP00000357113.4, ENST00000368131.8
- Conserved Domains (3) summary
-
- PTZ00449
Location:100 → 215
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- cd08305
Location:10 → 83
- Pyrin; a protein-protein interaction domain
- pfam02760
Location:201 → 369
- HIN; HIN-200/IF120x domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
158999976..159055151
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047419411.1 → XP_047275367.1 gamma-interferon-inducible protein 16 isoform X2
-
XM_047419406.1 → XP_047275362.1 gamma-interferon-inducible protein 16 isoform X1
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XM_047419399.1 → XP_047275355.1 gamma-interferon-inducible protein 16 isoform X1
-
XM_047419413.1 → XP_047275369.1 gamma-interferon-inducible protein 16 isoform X2
RNA
-
XR_007059344.1 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
158137044..158192189
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)