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RTL5 retrotransposon Gag like 5 [ Homo sapiens (human) ]

Gene ID: 340526, updated on 11-Jun-2021

Summary

Official Symbol
RTL5provided by HGNC
Official Full Name
retrotransposon Gag like 5provided by HGNC
Primary source
HGNC:HGNC:29430
See related
Ensembl:ENSG00000242732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAR5; MART5; RGAG4; SIRH8; 6430402L03Rik
Expression
Broad expression in brain (RPKM 6.6), testis (RPKM 6.2) and 24 other tissues See more
Orthologs
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Genomic context

See RTL5 in Genome Data Viewer
Location:
Xq13.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (72127110..72131915, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (71346960..71351765, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene NHS like 2 Neighboring gene Sharpr-MPRA regulatory region 1584 Neighboring gene ribosomal protein S26 pseudogene 11 Neighboring gene NHS like 2 Neighboring gene RNA, 7SL, cytoplasmic 388, pseudogene Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of retrotransposon gag domain containing 4 (RGAG4) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA2001

General protein information

Preferred Names
retrotransposon Gag-like protein 5
Names
Sushi-Ichi retrotransposon homolog 8
mammalian retrotransposon-derived 5
retrotransposon gag domain containing 4
retrotransposon gag domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021352.1 RefSeqGene

    Range
    4987..9792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001024455.4NP_001019626.1  retrotransposon Gag-like protein 5

    See identical proteins and their annotated locations for NP_001019626.1

    Status: VALIDATED

    Source sequence(s)
    AB082532, BC151224, BX119917
    Consensus CDS
    CCDS55446.1
    UniProtKB/Swiss-Prot
    Q5HYW3
    Related
    ENSP00000418667.1, ENST00000479991.1
    Conserved Domains (2) summary
    pfam03732
    Location:190282
    Retrotrans_gag; Retrotransposon gag protein
    pfam16297
    Location:151228
    DUF4939; Domain of unknown function (DUF4939)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    72127110..72131915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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