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LRRC30 leucine rich repeat containing 30 [ Homo sapiens (human) ]

Gene ID: 339291, updated on 13-May-2022

Summary

Official Symbol
LRRC30provided by HGNC
Official Full Name
leucine rich repeat containing 30provided by HGNC
Primary source
HGNC:HGNC:30219
See related
Ensembl:ENSG00000206422 AllianceGenome:HGNC:30219
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See LRRC30 in Genome Data Viewer
Location:
18p11.23
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (7231089..7232044)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (7394203..7395158)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (7231087..7232042)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr18:7038146-7039345 Neighboring gene SLC25A51 pseudogene 2 Neighboring gene uncharacterized LOC105371973 Neighboring gene uncharacterized LOC105371974

Genomic regions, transcripts, and products

General gene information

Markers

Homology

General protein information

Preferred Names
leucine-rich repeat-containing protein 30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105581.3NP_001099051.1  leucine-rich repeat-containing protein 30

    See identical proteins and their annotated locations for NP_001099051.1

    Status: VALIDATED

    Source sequence(s)
    AP005270
    Consensus CDS
    CCDS42409.1
    UniProtKB/Swiss-Prot
    A6NM36
    Related
    ENSP00000372959.2, ENST00000383467.3
    Conserved Domains (4) summary
    sd00031
    Location:257277
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:7395
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:141179
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:94173
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    7231089..7232044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    7394203..7395158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)