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HSP90AA2P heat shock protein 90 alpha family class A member 2, pseudogene [ Homo sapiens (human) ]

Gene ID: 3324, updated on 25-Jan-2024

Summary

Official Symbol
HSP90AA2Pprovided by HGNC
Official Full Name
heat shock protein 90 alpha family class A member 2, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:5256
See related
MIM:140575; AllianceGenome:HGNC:5256
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSPCA; HSPCAL3; HSP90AA2; HSP90ALPHA
Summary
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90AA2 is a cytosolic HSP90 protein. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]). See HSP90AA1 (MIM 140571) for further information on HSP90 proteins.[supplied by OMIM, Aug 2008]
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Genomic context

See HSP90AA2P in Genome Data Viewer
Location:
11p14.1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (27888171..27891092, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (28028805..28031726, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27909718..27912639, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:27743527-27744035 Neighboring gene uncharacterized LOC124902652 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:27762065-27762756 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:27817576-27818442 Neighboring gene CBX3 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4546 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4547 Neighboring gene uncharacterized LOC124902653 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:27955621-27956820 Neighboring gene uncharacterized LOC124902654

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • heat shock 90kD protein, alpha-like 3
  • heat shock 90kDa protein 1, alpha-like 3
  • heat shock protein 86
  • heat shock protein 90kDa alpha (cytosolic), class A member 1 pseudogene
  • heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
  • heat shock protein 90kDa alpha family class A member 2, pseudogene

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 
enables disordered domain specific binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular exosome HDA PubMed 
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005856.3 

    Range
    101..3022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    27888171..27891092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    28028805..28031726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001040141.1: Suppressed sequence

    Description
    NM_001040141.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.