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Opcml opioid binding protein/cell adhesion molecule-like [ Mus musculus (house mouse) ]

Gene ID: 330908, updated on 2-Apr-2024

Summary

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Official Symbol
Opcmlprovided by MGI
Official Full Name
opioid binding protein/cell adhesion molecule-likeprovided by MGI
Primary source
MGI:MGI:97397
See related
Ensembl:ENSMUSG00000062257 AllianceGenome:MGI:97397
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm181; Obcam; 3732419F12; C230027C17; 2900075O15Rik; B930023M13Rik
Summary
Is expressed in central nervous system; dorsal root ganglion; tongue; and trigeminal nerve. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human OPCML (opioid binding protein/cell adhesion molecule like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 13.6), cortex adult (RPKM 13.0) and 4 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 A4; 9 13.73 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (27702050..28836706)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (27790716..28925410)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23627 Neighboring gene STARR-seq mESC enhancer starr_23628 Neighboring gene N(alpha)-acetyltransferase 20, NatB catalytic subunit pseudogene Neighboring gene STARR-seq mESC enhancer starr_23629 Neighboring gene voltage-dependent anion channel 1 pseudogene Neighboring gene predicted gene, 39314 Neighboring gene STARR-seq mESC enhancer starr_23630 Neighboring gene STARR-seq mESC enhancer starr_23631 Neighboring gene STARR-seq mESC enhancer starr_23632 Neighboring gene STARR-seq mESC enhancer starr_23633 Neighboring gene predicted gene, 53502 Neighboring gene predicted gene, 33456 Neighboring gene STARR-seq mESC enhancer starr_23635 Neighboring gene predicted gene, 39313 Neighboring gene STARR-seq mESC enhancer starr_23636 Neighboring gene STARR-seq mESC enhancer starr_23637 Neighboring gene STARR-seq mESC enhancer starr_23639 Neighboring gene STARR-seq mESC enhancer starr_23640 Neighboring gene STARR-seq mESC enhancer starr_23641 Neighboring gene STARR-seq mESC enhancer starr_23644 Neighboring gene STARR-seq mESC enhancer starr_23645 Neighboring gene STARR-seq mESC enhancer starr_23646 Neighboring gene STARR-seq mESC enhancer starr_23647 Neighboring gene predicted gene 15520 Neighboring gene neurotrimin Neighboring gene STARR-seq mESC enhancer starr_23648 Neighboring gene STARR-seq mESC enhancer starr_23649 Neighboring gene STARR-seq mESC enhancer starr_23651 Neighboring gene STARR-seq mESC enhancer starr_23652 Neighboring gene STARR-seq mESC enhancer starr_23653 Neighboring gene STARR-seq mESC enhancer starr_23654 Neighboring gene predicted gene 15521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression of ovarian tumour suppressor OPCML in the female CD-1 mouse reproductive tract. Fleming JS, et al. Reproduction, 2009 Apr. PMID 19176311, Free PMC Article
  2. Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects. Ye M, et al. Am J Med Genet A, 2014 Apr. PMID 24616287
  3. Genetic mapping of opioid binding protein gene(s) to mouse chromosome 9. Chakraborti A, et al. Mamm Genome, 1993. PMID 8439730
  4. Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Fearnley S, et al. Sci Rep, 2021 Oct 1. PMID 34599206, Free PMC Article
  5. Isolation, characterization, and chromosomal location of the mouse enamelysin gene. Caterina J, et al. Genomics, 1999 Dec 1. PMID 10610728

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC99974

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  

General protein information

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Preferred Names
opioid-binding protein/cell adhesion molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177906.5 → NP_808574.2  opioid-binding protein/cell adhesion molecule precursor

    See identical proteins and their annotated locations for NP_808574.2

    Status: VALIDATED

    Source sequence(s)
    AC102567, AC116523, AC154803, AC166352
    Consensus CDS
    CCDS22942.1
    UniProtKB/TrEMBL
    Q3TYL3, Q6DFY2
    Related
    ENSMUSP00000110898.3, ENSMUST00000115243.9
    Conserved Domains (4) summary
    smart00408
    Location:142 → 198
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:226 → 304
    IG_like; Immunoglobulin like
    pfam00047
    Location:219 → 303
    ig; Immunoglobulin domain
    cl11960
    Location:37 → 125
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    27702050..28836706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155074.1 → XP_036010967.1  opioid-binding protein/cell adhesion molecule isoform X9

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  2. XM_036155073.1 → XP_036010966.1  opioid-binding protein/cell adhesion molecule isoform X7

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:216 → 293
    Ig_3; Immunoglobulin domain
    cd00096
    Location:217 → 223
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:37 → 125
    Ig; Immunoglobulin domain

  3. XM_036155078.1 → XP_036010971.1  opioid-binding protein/cell adhesion molecule isoform X12

    Conserved Domains (3) summary
    smart00409
    Location:2 → 32
    IG; Immunoglobulin
    pfam13927
    Location:122 → 199
    Ig_3; Immunoglobulin domain
    cd00096
    Location:123 → 129
    Ig; putative Ig strand A [structural motif]

  4. XM_036155077.1 → XP_036010970.1  opioid-binding protein/cell adhesion molecule isoform X11

    Conserved Domains (3) summary
    smart00409
    Location:2 → 32
    IG; Immunoglobulin
    pfam13927
    Location:123 → 200
    Ig_3; Immunoglobulin domain
    cd00096
    Location:124 → 130
    Ig; putative Ig strand A [structural motif]

  5. XM_036155072.1 → XP_036010965.1  opioid-binding protein/cell adhesion molecule isoform X4

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:215 → 292
    Ig_3; Immunoglobulin domain
    cd00096
    Location:216 → 222
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:37 → 125
    Ig; Immunoglobulin domain

  6. XM_030244423.2 → XP_030100283.1  opioid-binding protein/cell adhesion molecule isoform X3

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:216 → 293
    Ig_3; Immunoglobulin domain
    cd00096
    Location:217 → 223
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:37 → 125
    Ig; Immunoglobulin domain

  7. XM_036155076.1 → XP_036010969.1  opioid-binding protein/cell adhesion molecule isoform X10

    Conserved Domains (3) summary
    smart00409
    Location:2 → 32
    IG; Immunoglobulin
    pfam13927
    Location:123 → 200
    Ig_3; Immunoglobulin domain
    cd00096
    Location:124 → 130
    Ig; putative Ig strand A [structural motif]

  8. XM_006510439.5 → XP_006510502.1  opioid-binding protein/cell adhesion molecule isoform X8

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:182 → 259
    Ig_3; Immunoglobulin domain
    cd00096
    Location:183 → 189
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  9. XM_006510435.5 → XP_006510498.1  opioid-binding protein/cell adhesion molecule isoform X2

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  10. XM_006510434.5 → XP_006510497.1  opioid-binding protein/cell adhesion molecule isoform X1

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:223 → 300
    Ig_3; Immunoglobulin domain
    cd00096
    Location:224 → 230
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  11. XM_036155075.1 → XP_036010968.1  opioid-binding protein/cell adhesion molecule isoform X9

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  12. XM_006510438.5 → XP_006510501.1  opioid-binding protein/cell adhesion molecule isoform X6

    See identical proteins and their annotated locations for XP_006510501.1

    UniProtKB/TrEMBL
    Q3TYL3
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  13. XM_006510437.5 → XP_006510500.1  opioid-binding protein/cell adhesion molecule isoform X5

    See identical proteins and their annotated locations for XP_006510500.1

    UniProtKB/TrEMBL
    G5E8G3, Q3TYL3
    Related
    ENSMUSP00000073493.6, ENSMUST00000073822.6
    Conserved Domains (3) summary
    pfam13927
    Location:223 → 300
    Ig_3; Immunoglobulin domain
    cd00096
    Location:224 → 230
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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