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Saxo2 stabilizer of axonemal microtubules 2 [ Mus musculus (house mouse) ]

Gene ID: 330577, updated on 11-Apr-2024

Summary

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Official Symbol
Saxo2provided by MGI
Official Full Name
stabilizer of axonemal microtubules 2provided by MGI
Primary source
MGI:MGI:1914618
See related
Ensembl:ENSMUSG00000038570 AllianceGenome:MGI:1914618
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam154b; D030069K18; 1700129I04Rik
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Is active in nucleus. Is expressed in lateral ventricle choroid plexus; lung epithelium; nasal cavity respiratory epithelium; and nasopharynx epithelium. Orthologous to human SAXO2 (stabilizer of axonemal microtubules 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 8.1), lung adult (RPKM 0.7) and 7 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 D3; 7 47.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (82282166..82297777, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (82632960..82648561, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene SH3-domain GRB2-like 3 Neighboring gene predicted gene, 51492 Neighboring gene ADAMTS-like 3 Neighboring gene VISTA enhancer mm1514 Neighboring gene elongation factor like GTPase 1 Neighboring gene RIKEN cDNA 4933406J10 gene Neighboring gene STARR-seq mESC enhancer starr_19388 Neighboring gene predicted gene, 29796

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
stabilizer of axonemal microtubules 2
Names
family with sequence similarity 154, member B
protein FAM154B
stablizer of axonemal microtubules 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001415796.1 → NP_001402725.1  stabilizer of axonemal microtubules 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC138270

  2. NM_177894.5 → NP_808562.3  stabilizer of axonemal microtubules 2 isoform 2

    See identical proteins and their annotated locations for NP_808562.3

    Status: VALIDATED

    Source sequence(s)
    AC138270
    Consensus CDS
    CCDS21409.1
    UniProtKB/Swiss-Prot
    G3X9C9, Q8BQB6
    Related
    ENSMUSP00000057993.4, ENSMUST00000056728.5

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    82282166..82297777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241834.3 → XP_011240136.1  stabilizer of axonemal microtubules 2 isoform X2

  2. XM_030242693.2 → XP_030098553.1  stabilizer of axonemal microtubules 2 isoform X1

  3. XM_030242694.1 → XP_030098554.1  stabilizer of axonemal microtubules 2 isoform X3

    UniProtKB/TrEMBL
    Q8CAI4
    Related
    ENSMUST00000151632.8
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BQB6.2 GenPept UniProtKB/Swiss-Prot:Q8BQB6

Gene LinkOut

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