Format

Send to:

Choose Destination

SAXO2 stabilizer of axonemal microtubules 2 [ Homo sapiens (human) ]

Gene ID: 283726, updated on 5-Jan-2022

Summary

Official Symbol
SAXO2provided by HGNC
Official Full Name
stabilizer of axonemal microtubules 2provided by HGNC
Primary source
HGNC:HGNC:33727
See related
Ensembl:ENSG00000188659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM154B
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be active in microtubule cytoskeleton; nucleus; and sperm flagellum. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in lung (RPKM 3.6), testis (RPKM 1.5) and 13 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SAXO2 in Genome Data Viewer
Location:
15q25.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (82262818..82284930)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (82555159..82577268)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370924 Neighboring gene long intergenic non-protein coding RNA 1583 Neighboring gene elongation factor like GTPase 1 Neighboring gene RNA, U1 small nuclear 77, pseudogene Neighboring gene ADAMTS7 pseudogene 1 Neighboring gene dynamin 1 pseudogene 43

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • DKFZp666G057

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule anchoring IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
stabilizer of axonemal microtubules 2
Names
family with sequence similarity 154, member B
protein FAM154B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008226.2NP_001008227.1  stabilizer of axonemal microtubules 2 isoform c

    See identical proteins and their annotated locations for NP_001008227.1

    Status: VALIDATED

    Source sequence(s)
    AL833762
    Consensus CDS
    CCDS32310.1
    UniProtKB/Swiss-Prot
    Q658L1
    Related
    ENSP00000340445.5, ENST00000339465.5
  2. NM_001348699.2NP_001335628.1  stabilizer of axonemal microtubules 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AC026624, DB233386
    Related
    ENSP00000508095.1, ENST00000682753.1
  3. NM_001348700.2NP_001335629.1  stabilizer of axonemal microtubules 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 3, encodes isoform b.
    Source sequence(s)
    AC026624
  4. NM_001348701.2NP_001335630.1  stabilizer of axonemal microtubules 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variant 2, encodes isoform b.
    Source sequence(s)
    AC026624, DB215297
  5. NM_001348702.2NP_001335631.1  stabilizer of axonemal microtubules 2 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variant 6, encodes isoform d.
    Source sequence(s)
    AC026624
    UniProtKB/Swiss-Prot
    Q658L1
  6. NM_001348703.2NP_001335632.1  stabilizer of axonemal microtubules 2 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variant 5, encodes isoform d.
    Source sequence(s)
    AC026624, AK304339
    UniProtKB/Swiss-Prot
    Q658L1
  7. NM_001348704.2NP_001335633.1  stabilizer of axonemal microtubules 2 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC026624
  8. NM_001348705.2NP_001335634.1  stabilizer of axonemal microtubules 2 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC026624, BF942184, BX090922
    Related
    ENST00000562097.5
  9. NM_001348706.2NP_001335635.1  stabilizer of axonemal microtubules 2 isoform g

    Status: VALIDATED

    Source sequence(s)
    AC026624

RNA

  1. NR_145958.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026624, AI634060, BX090922
    Related
    ENST00000566205.1
  2. NR_145959.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026624, BX090922
    Related
    ENST00000566861.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    82262818..82284930
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449902.1XP_024305670.1  stabilizer of axonemal microtubules 2 isoform X1

  2. XM_024449903.1XP_024305671.1  stabilizer of axonemal microtubules 2 isoform X2

Support Center