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Mpzl3 myelin protein zero-like 3 [ Mus musculus (house mouse) ]

Gene ID: 319742, updated on 12-May-2024

Summary

Official Symbol
Mpzl3provided by MGI
Official Full Name
myelin protein zero-like 3provided by MGI
Primary source
MGI:MGI:2442647
See related
Ensembl:ENSMUSG00000070305 AllianceGenome:MGI:2442647
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
rc; ruf; 5430427F17Rik; A530065I17Rik
Summary
Acts upstream of or within extracellular matrix organization and hair cycle. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human MPZL3 (myelin protein zero like 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 4.2), small intestine adult (RPKM 3.4) and 27 other tissues See more
Orthologs
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Genomic context

See Mpzl3 in Genome Data Viewer
Location:
9 A5.2; 9 24.84 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44966479..44988735)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (45055181..45077437)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CD3 antigen, epsilon polypeptide Neighboring gene STARR-seq mESC enhancer starr_23989 Neighboring gene STARR-positive B cell enhancer mm9_chr9:44849180-44849480 Neighboring gene myelin protein zero-like 2 Neighboring gene STARR-seq mESC enhancer starr_23990 Neighboring gene junction adhesion molecule like Neighboring gene predicted gene 10684 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:44929112-44929313 Neighboring gene sodium channel, voltage-gated, type II, beta

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
rough coat
GeneReviews: Not available
rough fur
GeneReviews: Not available

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 
  • Spontaneous (3) 
  • Targeted (2)  1 citation

General protein information

Preferred Names
myelin protein zero-like protein 3
Names
Ig-like domain-containing protein UNQ2966

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093749.3NP_001087218.1  myelin protein zero-like protein 3 precursor

    See identical proteins and their annotated locations for NP_001087218.1

    Status: VALIDATED

    Source sequence(s)
    AC122305, EF102773
    Consensus CDS
    CCDS52781.1
    UniProtKB/Swiss-Prot
    A5H7F1, Q3V3F6
    Related
    ENSMUSP00000110312.3, ENSMUST00000114664.8
    Conserved Domains (2) summary
    smart00410
    Location:40148
    IG_like; Immunoglobulin like
    cl11960
    Location:34137
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    44966479..44988735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_176993.3: Suppressed sequence

    Description
    NM_176993.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.