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H2bc12 H2B clustered histone 12 [ Mus musculus (house mouse) ]

Gene ID: 319184, updated on 5-Jan-2023

Summary

Official Symbol
H2bc12provided by MGI
Official Full Name
H2B clustered histone 12provided by MGI
Primary source
MGI:MGI:2448399
See related
Ensembl:ENSMUSG00000062727 AllianceGenome:MGI:2448399
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hist1h2bk
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. [provided by RefSeq, Aug 2015]
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Genomic context

See H2bc12 in Genome Data Viewer
Location:
13; 13 A3.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (22219991..22220490)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (22035821..22036320)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA threonine 1 (anticodon AGT) Neighboring gene H2A clustered histone 12 Neighboring gene H4 clustered histone 9 Neighboring gene H2A clustered histone 11

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H2B type 1-K
Names
histone 1, H2bk
histone cluster 1, H2bk

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175665.2NP_783596.1  histone H2B type 1-K

    See identical proteins and their annotated locations for NP_783596.1

    Status: REVIEWED

    Source sequence(s)
    AL590614
    Consensus CDS
    CCDS26305.1
    UniProtKB/Swiss-Prot
    Q8CGP1
    UniProtKB/TrEMBL
    B2RVD5
    Related
    ENSMUSP00000106085.3, ENSMUST00000110455.4
    Conserved Domains (2) summary
    smart00427
    Location:28124
    H2B; Histone H2B
    pfam00125
    Location:3102
    Histone; Core histone H2A/H2B/H3/H4

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    22219991..22220490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)