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H2bc7 H2B clustered histone 7 [ Mus musculus (house mouse) ]

Gene ID: 319180, updated on 8-Feb-2024

Summary

Official Symbol
H2bc7provided by MGI
Official Full Name
H2B clustered histone 7provided by MGI
Primary source
MGI:MGI:2448383
See related
Ensembl:ENSMUSG00000069268 AllianceGenome:MGI:2448383
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2bc11; H2bc13; H2bc15; Hist1h2bf
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

See H2bc7 in Genome Data Viewer
Location:
13 A3.1; 13 9.8 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23757934..23758381, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23573760..23574207, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2400 Neighboring gene H2A clustered histone 8 Neighboring gene H2B clustered histone 8 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23666001-23666302 Neighboring gene H2A clustered histone 7 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23667191-23667492 Neighboring gene H3 clustered histone 4

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H2B type 1-F/J/L
Names
H2B 291A
histone 1, H2bf
histone cluster 1, H2bf

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178195.3NP_835502.1  histone H2B type 1-F/J/L

    See identical proteins and their annotated locations for NP_835502.1

    Status: REVIEWED

    Source sequence(s)
    AL592149
    Consensus CDS
    CCDS26350.1
    UniProtKB/Swiss-Prot
    P10853, Q5SZZ3
    UniProtKB/TrEMBL
    A0JLV3
    Related
    ENSMUSP00000100738.2, ENSMUST00000105106.2
    Conserved Domains (1) summary
    smart00427
    Location:28124
    H2B; Histone H2B

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    23757934..23758381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)