U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Jhy junctional cadherin complex regulator [ Rattus norvegicus (Norway rat) ]

Gene ID: 315578, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Jhyprovided by RGD
Official Full Name
junctional cadherin complex regulatorprovided by RGD
Primary source
RGD:1309108
See related
EnsemblRapid:ENSRNOG00000008138 AllianceGenome:RGD:1309108
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309108
Summary
Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; cilium assembly; and regulation of establishment of planar polarity. Predicted to be located in extracellular region. Orthologous to human JHY (junctional cadherin complex regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 38.8), Brain (RPKM 12.2) and 1 other tissue See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
8q22
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (50173602..50230429, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (41276501..41333383, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (45084067..45140570, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 2, pseudogene 1 Neighboring gene brain specific homeobox Neighboring gene uncharacterized LOC134480158 Neighboring gene uncharacterized LOC134480157 Neighboring gene cytotoxic and regulatory T cell molecule Neighboring gene ubiquitin associated and SH3 domain containing, B Neighboring gene uncharacterized LOC134480159

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus. Appelbe OK, et al. Dev Biol, 2013 Oct 1. PMID 23906841, Free PMC Article
  2. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within brain development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cell differentiation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cerebrospinal fluid circulation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within establishment of localization in cell ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within motile cilium assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of establishment of planar polarity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
jhy protein homolog; junctional cadherin complex regulator
Names
juvenile hydrocephalus
uncharacterized protein C11orf63 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429449.1 → NP_001416378.1  junctional cadherin complex regulator isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

  2. NM_001429450.1 → NP_001416379.1  junctional cadherin complex regulator isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    F1LZA7

  3. NM_001429451.1 → NP_001416380.1  junctional cadherin complex regulator isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    F1LZA7

  4. NM_001429452.1 → NP_001416381.1  junctional cadherin complex regulator isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    F1LZA7

  5. NM_001429453.1 → NP_001416382.1  junctional cadherin complex regulator isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    50173602..50230429 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039082325.2 → XP_038938253.1  jhy protein homolog isoform X1

    Related
    ENSRNOP00000010743.9, ENSRNOT00000010743.9
    Conserved Domains (1) summary
    pfam15261
    Location:654 → 773
    DUF4591; Domain of unknown function (DUF4591)

  2. XM_039082327.2 → XP_038938255.1  jhy protein homolog isoform X2

    Conserved Domains (1) summary
    pfam15261
    Location:650 → 769
    DUF4591; Domain of unknown function (DUF4591)

  3. XM_039082328.2 → XP_038938256.1  jhy protein homolog isoform X2

    Conserved Domains (1) summary
    pfam15261
    Location:650 → 769
    DUF4591; Domain of unknown function (DUF4591)

  4. XM_039082326.2 → XP_038938254.1  jhy protein homolog isoform X2

    Related
    ENSRNOP00000106527.1, ENSRNOT00000131570.1
    Conserved Domains (1) summary
    pfam15261
    Location:650 → 769
    DUF4591; Domain of unknown function (DUF4591)

  5. XM_039082329.2 → XP_038938257.1  jhy protein homolog isoform X3

    Conserved Domains (1) summary
    pfam15261
    Location:491 → 610
    DUF4591; Domain of unknown function (DUF4591)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials