Format

Send to:

Choose Destination

JHY junctional cadherin complex regulator [ Homo sapiens (human) ]

Gene ID: 79864, updated on 13-Mar-2020

Summary

Official Symbol
JHYprovided by HGNC
Official Full Name
junctional cadherin complex regulatorprovided by HGNC
Primary source
HGNC:HGNC:26288
See related
Ensembl:ENSG00000109944 MIM:617594
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C11orf63
Expression
Broad expression in testis (RPKM 7.4), kidney (RPKM 1.8) and 16 other tissues See more
Orthologs

Genomic context

See JHY in Genome Data Viewer
Location:
11q24.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (122882528..122963862)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (122753236..122830430)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ubiquitin associated and SH3 domain containing B Neighboring gene cytotoxic and regulatory T cell molecule Neighboring gene RNA, U4 small nuclear 23, pseudogene Neighboring gene ATP synthase peripheral stalk-membrane subunit b pseudogene 5 Neighboring gene brain specific homeobox Neighboring gene SUMO1 activating enzyme subunit 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23554

Gene Ontology Provided by GOA

Process Evidence Code Pubs
axoneme assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
brain development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cerebrospinal fluid secretion IEA
Inferred from Electronic Annotation
more info
 
ciliary basal body organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
jhy protein homolog
Names
juvenile hydrocephalus
uncharacterized protein C11orf63

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363087.1NP_001350016.1  jhy protein homolog isoform 3

    Status: VALIDATED

    Source sequence(s)
    AP003040, AP004318
    Conserved Domains (1) summary
    pfam15261
    Location:645745
    DUF4591; Domain of unknown function (DUF4591)
  2. NM_001363088.1NP_001350017.1  jhy protein homolog isoform 4

    Status: VALIDATED

    Source sequence(s)
    AP003040, AP004318
    Conserved Domains (1) summary
    pfam15261
    Location:622734
    DUF4591; Domain of unknown function (DUF4591)
  3. NM_001363089.1NP_001350018.1  jhy protein homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AP003040, AP004318
    Consensus CDS
    CCDS8438.1
    Related
    ENSP00000431669.1, ENST00000531316.1
    Conserved Domains (1) summary
    pfam15261
    Location:660772
    DUF4591; Domain of unknown function (DUF4591)
  4. NM_024806.4NP_079082.2  jhy protein homolog isoform 1

    See identical proteins and their annotated locations for NP_079082.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AP003040, AP004318, BC068507
    Consensus CDS
    CCDS8438.1
    UniProtKB/Swiss-Prot
    Q6NUN7
    Related
    ENSP00000227349.2, ENST00000227349.7
    Conserved Domains (1) summary
    pfam15261
    Location:660772
    DUF4591; Domain of unknown function (DUF4591)
  5. NM_199124.2NP_954575.1  jhy protein homolog isoform 2

    See identical proteins and their annotated locations for NP_954575.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks several exons but has an alternate 3' terminal exon, compared to variant 1. The resulting isoform (2) is much shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK097534, AP004318, BC009820
    Consensus CDS
    CCDS8439.1
    UniProtKB/Swiss-Prot
    Q6NUN7
    UniProtKB/TrEMBL
    B3KUM2
    Related
    ENSP00000307695.5, ENST00000307257.10

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    122882528..122963862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center