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Mettl25 methyltransferase like 25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314798, updated on 3-Apr-2024

Summary

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Official Symbol
Mettl25provided by RGD
Official Full Name
methyltransferase like 25provided by RGD
Primary source
RGD:1310270
See related
Ensembl:ENSRNOG00000027451 AllianceGenome:RGD:1310270
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310270
Summary
Orthologous to human METTL25 (methyltransferase like 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 68.2), Lung (RPKM 61.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
7q21
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (42948934..43029610, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (41062276..41143056, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (47847812..47928495, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene transmembrane O-mannosyltransferase targeting cadherins 2 Neighboring gene uncharacterized LOC120093578 Neighboring gene uncharacterized LOC134479681 Neighboring gene coiled-coil domain containing 59 Neighboring gene uncharacterized LOC134479682 Neighboring gene PTPRF interacting protein alpha 2 Neighboring gene sulfotransferase 1C2 pseudogene Neighboring gene acyl-CoA synthetase short-chain family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
probable methyltransferase-like protein 25
Names
methyltransferase-like protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108089.1 → NP_001101559.1  probable methyltransferase-like protein 25

    See identical proteins and their annotated locations for NP_001101559.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    A0A8I5Y618, B1WC27
    Related
    ENSRNOP00000029686.5, ENSRNOT00000038144.6
    Conserved Domains (1) summary
    cl17173
    Location:152 → 414
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    42948934..43029610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079101.2 → XP_038935029.2  probable methyltransferase-like protein 25 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GC39

  2. XM_039079105.2 → XP_038935033.1  probable methyltransferase-like protein 25 isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZNA4
    Conserved Domains (2) summary
    PTZ00098
    Location:50 → 95
    PTZ00098; phosphoethanolamine N-methyltransferase; Provisional
    cl17173
    Location:225 → 289
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_063263473.1 → XP_063119543.1  probable methyltransferase-like protein 25 isoform X5

  4. XM_063263472.1 → XP_063119542.1  probable methyltransferase-like protein 25 isoform X3

  5. XM_063263470.1 → XP_063119540.1  probable methyltransferase-like protein 25 isoform X2

RNA

  1. XR_010052971.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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