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Golim4 golgi integral membrane protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310526, updated on 17-Aug-2024

Summary

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Official Symbol
Golim4provided by RGD
Official Full Name
golgi integral membrane protein 4provided by RGD
Primary source
RGD:1310948
See related
EnsemblRapid:ENSRNOG00000024213 AllianceGenome:RGD:1310948
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Golph4
Summary
Predicted to be located in Golgi cisterna membrane; Golgi membrane; and endosome membrane. Predicted to be active in Golgi apparatus. Predicted to be integral component of membrane. Orthologous to human GOLIM4 (golgi integral membrane protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 157.8), Lung (RPKM 135.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
2q32
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (162939429..163031901, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (160640837..160733475, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (174321303..174413847, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC108350036 Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 46 Neighboring gene uncharacterized LOC102547227 Neighboring gene follistatin-like 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Sequence and overexpression of GPP130/GIMPc: evidence for saturable pH-sensitive targeting of a type II early Golgi membrane protein. Linstedt AD, et al. Mol Biol Cell, 1997 Jun. PMID 9201717, Free PMC Article
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
Golgi integral membrane protein 4
Names
GIMPc
golgi integral membrane protein, cis
golgi phosphoprotein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399468.1 → NP_001386397.1  Golgi integral membrane protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    D3ZM57
    Related
    ENSRNOP00000103794.1, ENSRNOT00000136886.1
    Conserved Domains (2) summary
    pfam10186
    Location:108 → 248
    Atg14; Vacuolar sorting 38 and autophagy-related subunit 14
    NF012221
    Location:174 → 555
    MARTX_Nterm; MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region

  2. NM_001399469.1 → NP_001386398.1  Golgi integral membrane protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    Q5BJK8
    UniProtKB/TrEMBL
    D3ZM57
    Related
    ENSRNOP00000035176.3, ENSRNOT00000037115.7
    Conserved Domains (2) summary
    COG1196
    Location:33 → 309
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    NF012221
    Location:243 → 527
    MARTX_Nterm; MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    162939429..163031901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001191567.1: Suppressed sequence

    Description
    NM_001191567.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BJK8.2 GenPept UniProtKB/Swiss-Prot:Q5BJK8

Gene LinkOut

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