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C3h15orf48 similar to human chromosome 15 open reading frame 48 [ Rattus norvegicus (Norway rat) ]

Gene ID: 302884, updated on 19-Sep-2024

Summary

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Official Symbol
C3h15orf48provided by RGD
Official Full Name
similar to human chromosome 15 open reading frame 48provided by RGD
Primary source
RGD:1359583
See related
EnsemblRapid:ENSRNOG00000067060 AllianceGenome:RGD:1359583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nmes1
Summary
Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleus. Predicted to be part of mitochondrial respiratory chain complex IV. Orthologous to human C15orf48 (chromosome 15 open reading frame 48). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 173.2), Spleen (RPKM 94.1) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
3q35
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (130173535..130177088)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (109719952..109723505)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (114772603..114776156)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene glycine amidinotransferase Neighboring gene AFG2 AAA ATPase homolog B Neighboring gene microRNA 147 Neighboring gene solute carrier family 30 member 4 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel gene, NMES1, downregulated in human esophageal squamous cell carcinoma. Zhou J, et al. Int J Cancer, 2002 Oct 1. PMID 12209954
  2. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC105649

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within response to bacterium ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
part_of respiratory chain complex IV IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
normal mucosa of esophagus-specific gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008518.2 → NP_001008518.1  normal mucosa of esophagus-specific gene 1 protein

    See identical proteins and their annotated locations for NP_001008518.1

    Status: VALIDATED

    Source sequence(s)
    BC086337, CB585387
    UniProtKB/Swiss-Prot
    Q5RK28
    Related
    ENSRNOP00000106877.1, ENSRNOT00000073569.3
    Conserved Domains (1) summary
    pfam06522
    Location:9 → 76
    B12D; NADH-ubiquinone reductase complex 1 MLRQ subunit

  2. NM_001395676.1 → NP_001382605.1  normal mucosa of esophagus-specific gene 1 protein

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q5RK28
    Conserved Domains (1) summary
    pfam06522
    Location:9 → 76
    B12D; NADH-ubiquinone reductase complex 1 MLRQ subunit

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    130173535..130177088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RK28.1 GenPept UniProtKB/Swiss-Prot:Q5RK28

Gene LinkOut

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