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Timm10 translocase of inner mitochondrial membrane 10 [ Mus musculus (house mouse) ]

Gene ID: 30059, updated on 5-Mar-2024

Summary

Official Symbol
Timm10provided by MGI
Official Full Name
translocase of inner mitochondrial membrane 10provided by MGI
Primary source
MGI:MGI:1353429
See related
Ensembl:ENSMUSG00000027076 AllianceGenome:MGI:1353429
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tim13; Timm13a
Summary
Predicted to enable chaperone binding activity; membrane insertase activity; and protein homodimerization activity. Involved in protein insertion into mitochondrial inner membrane. Located in mitochondrion. Part of mitochondrial intermembrane space protein transporter complex. Is expressed in genitourinary system and liver. Orthologous to human TIMM10 (translocase of inner mitochondrial membrane 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 34.3), CNS E18 (RPKM 29.3) and 28 other tissues See more
Orthologs
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Genomic context

Location:
2 D; 2 49.45 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (84657365..84660557)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (84827021..84830213)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1592 Neighboring gene ubiquitin-conjugating enzyme E2L 6 Neighboring gene STARR-seq mESC enhancer starr_05011 Neighboring gene smoothelin-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E2628 Neighboring gene RIKEN cDNA D930003E18 gene Neighboring gene solute carrier family 43, member 1 Neighboring gene reticulon 4 receptor-like 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables membrane insertase activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein-folding chaperone binding ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial import inner membrane translocase subunit Tim10
Names
translocase of inner mitochondrial membrane 10 homolog
translocase of inner mitochondrial membrane 13 homolog a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013899.2NP_038927.2  mitochondrial import inner membrane translocase subunit Tim10

    See identical proteins and their annotated locations for NP_038927.2

    Status: VALIDATED

    Source sequence(s)
    AF150090, AK008088, AK013546
    Consensus CDS
    CCDS38161.1
    UniProtKB/Swiss-Prot
    P62073
    Related
    ENSMUSP00000028470.4, ENSMUST00000028470.10
    Conserved Domains (1) summary
    pfam02953
    Location:769
    zf-Tim10_DDP; Tim10/DDP family zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    84657365..84660557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)